Machine Protection and Operation for LHC

Since 2010 the Large Hadron Collider (LHC) is the accelerator with the highest stored energy per beam, with a record of 140 MJ at a beam energy of 4 TeV, almost a factor of 50 higher than other accelerators. With such a high stored energy, machine protection aspects set the boundary conditions for operation during all phases of the machine cycle. Only the low-intensity commissioning beams can be considered as relatively safe. This document discusses the interplay of machine operation and machine protection at the LHC, from commissioning to regular operation.