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Mathematical modeling of protein complexes

This book is devoted to the physical and mathematical modeling of the formation of complexes of protein molecules. The models developed show remarkable sensitivity to the amino acid sequences of proteins, which facilitates experimental studies and allows one to reduce the associated costs by reducin...

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Detalles Bibliográficos
Autores principales: Koshlan, Tatiana, Kulikov, Kirill
Lenguaje:eng
Publicado: Springer 2018
Materias:
Acceso en línea:https://dx.doi.org/10.1007/978-3-319-98304-2
http://cds.cern.ch/record/2638867
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author Koshlan, Tatiana
Kulikov, Kirill
author_facet Koshlan, Tatiana
Kulikov, Kirill
author_sort Koshlan, Tatiana
collection CERN
description This book is devoted to the physical and mathematical modeling of the formation of complexes of protein molecules. The models developed show remarkable sensitivity to the amino acid sequences of proteins, which facilitates experimental studies and allows one to reduce the associated costs by reducing the number of measurements required according to the developed criteria. These models make it possible to reach a conclusion about the interactions between different amino acid chains and to identify more stable sites on proteins. The models also take the phosphorylation of amino acid residues into account. At the end of the book, the authors present possible directions of application of their physical and mathematical models in clinical medicine.
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spelling cern-26388672021-04-21T18:43:12Zdoi:10.1007/978-3-319-98304-2http://cds.cern.ch/record/2638867engKoshlan, TatianaKulikov, KirillMathematical modeling of protein complexesMathematical Physics and MathematicsThis book is devoted to the physical and mathematical modeling of the formation of complexes of protein molecules. The models developed show remarkable sensitivity to the amino acid sequences of proteins, which facilitates experimental studies and allows one to reduce the associated costs by reducing the number of measurements required according to the developed criteria. These models make it possible to reach a conclusion about the interactions between different amino acid chains and to identify more stable sites on proteins. The models also take the phosphorylation of amino acid residues into account. At the end of the book, the authors present possible directions of application of their physical and mathematical models in clinical medicine.Springeroai:cds.cern.ch:26388672018
spellingShingle Mathematical Physics and Mathematics
Koshlan, Tatiana
Kulikov, Kirill
Mathematical modeling of protein complexes
title Mathematical modeling of protein complexes
title_full Mathematical modeling of protein complexes
title_fullStr Mathematical modeling of protein complexes
title_full_unstemmed Mathematical modeling of protein complexes
title_short Mathematical modeling of protein complexes
title_sort mathematical modeling of protein complexes
topic Mathematical Physics and Mathematics
url https://dx.doi.org/10.1007/978-3-319-98304-2
http://cds.cern.ch/record/2638867
work_keys_str_mv AT koshlantatiana mathematicalmodelingofproteincomplexes
AT kulikovkirill mathematicalmodelingofproteincomplexes