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Terbium Radionuclides for Theranostics Applications: A Focus On MEDICIS-PROMED

A new facility, named CERN-MEDICIS, is under construction at CERN to produce radionuclides for medical applications. In parallel, the MEDICIS-PROMED, a Marie Sklodowska-Curie innovative training network of the Horizon 2020 European Commission‘s program, is being coordinated by CERN to train young sc...

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Detalles Bibliográficos
Autores principales: Formento Cavaiera, R, Haddadac, F, Sounalet, A, Stora, T, Zahib, I
Lenguaje:eng
Publicado: 2020
Acceso en línea:https://dx.doi.org/10.1016/j.phpro.2017.09.053
http://cds.cern.ch/record/2707707
Descripción
Sumario:A new facility, named CERN-MEDICIS, is under construction at CERN to produce radionuclides for medical applications. In parallel, the MEDICIS-PROMED, a Marie Sklodowska-Curie innovative training network of the Horizon 2020 European Commission‘s program, is being coordinated by CERN to train young scientists on the production and use of innovative radionuclides and develop a network of experts within Europe. One program within MEDICIS-PROMED is to determine the feasibility of producing innovative radioisotopes for theranostics using a commercial middle-sized high-current cyclotron and the mass separation technology developed at CERN-MEDICIS. This will allow the production of high specific activity radioisotopes not achievable with the common post-processing by chemical separation. Radioisotopes of scandium, copper, arsenic and terbium have been identified. Preliminary studies of activation yield and irradiation parameters optimization for the production of Tb-149 will be described.