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CLIC prototype on which the electron FLASH radiotherapy design is based

Technology developed for the proposed Compact Linear Collider (CLIC) at CERN is poised to make a novel cancer radio‑therapy facility a reality. Building on recently revived research from the 1970s, oncologists believe that ultrafast bursts of electrons damage tumours more than healthy tissue. This “...

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Autor principal: Ordan, Julien Marius
Publicado: 2022
Materias:
Acceso en línea:http://cds.cern.ch/record/2800803
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author Ordan, Julien Marius
author_facet Ordan, Julien Marius
author_sort Ordan, Julien Marius
collection CERN
description Technology developed for the proposed Compact Linear Collider (CLIC) at CERN is poised to make a novel cancer radio‑therapy facility a reality. Building on recently revived research from the 1970s, oncologists believe that ultrafast bursts of electrons damage tumours more than healthy tissue. This “FLASH effect” could be realised by using high-gradient accelerator technology from CLIC to create a new facility at Switzerland’s Lausanne University Hospital (CHUV). A 2014 study carried out by researchers from the CHUV hospital, and from the Institute Curie in Paris, showed an outstanding differential FLASH effect between tumours and normal tissues in mice. The results were later confirmed by several other leading institutes. Then, in 2019, CHUV used FLASH to treat a multi-resistant skin cancer in a human patient, causing the tumour to completely disappear with nearly no side effects.
id cern-2800803
institution Organización Europea para la Investigación Nuclear
publishDate 2022
record_format invenio
spelling cern-28008032022-02-22T08:52:57Zhttp://cds.cern.ch/record/2800803Ordan, Julien MariusCLIC prototype on which the electron FLASH radiotherapy design is basedPhotolabTechnology developed for the proposed Compact Linear Collider (CLIC) at CERN is poised to make a novel cancer radio‑therapy facility a reality. Building on recently revived research from the 1970s, oncologists believe that ultrafast bursts of electrons damage tumours more than healthy tissue. This “FLASH effect” could be realised by using high-gradient accelerator technology from CLIC to create a new facility at Switzerland’s Lausanne University Hospital (CHUV). A 2014 study carried out by researchers from the CHUV hospital, and from the Institute Curie in Paris, showed an outstanding differential FLASH effect between tumours and normal tissues in mice. The results were later confirmed by several other leading institutes. Then, in 2019, CHUV used FLASH to treat a multi-resistant skin cancer in a human patient, causing the tumour to completely disappear with nearly no side effects.CERN-PHOTO-202202-013oai:cds.cern.ch:28008032022
spellingShingle Photolab
Ordan, Julien Marius
CLIC prototype on which the electron FLASH radiotherapy design is based
title CLIC prototype on which the electron FLASH radiotherapy design is based
title_full CLIC prototype on which the electron FLASH radiotherapy design is based
title_fullStr CLIC prototype on which the electron FLASH radiotherapy design is based
title_full_unstemmed CLIC prototype on which the electron FLASH radiotherapy design is based
title_short CLIC prototype on which the electron FLASH radiotherapy design is based
title_sort clic prototype on which the electron flash radiotherapy design is based
topic Photolab
url http://cds.cern.ch/record/2800803
work_keys_str_mv AT ordanjulienmarius clicprototypeonwhichtheelectronflashradiotherapydesignisbased