A fully joint Bayesian quantitative trait locus mapping of human protein abundance in plasma

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Molecular quantitative trait locus (QTL) analyses are increasingly popular to explore the genetic architecture of complex traits, but existing studies do not leverage shared regulatory patterns and suffer from a large multiplicity burden, which hampers the detection of weak signals such as trans ass...

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Detalles Bibliográficos
Autores principales: Ruffieux, Hélène, Carayol, Jérôme, Popescu, Radu, Harper, Mary-Ellen, Dent, Robert, Saris, Wim H M, Astrup, Arne, Hager, Jörg, Davison, Anthony C, Valsesia, Armand
Lenguaje:eng
Publicado: 2020
Materias:
Computing and Computers
Health Physics and Radiation Effects
Acceso en línea:https://dx.doi.org/10.1371/journal.pcbi.1007882
http://cds.cern.ch/record/2801432
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