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Multi-energy spectral photon-counting computed tomography (MARS) for detection of arthroplasty implant failure

To determine whether state-of-the-art multi-energy spectral photon-counting computed tomography (MARS) can detect knee arthroplasty implant failure not detected by standard pre-operative imaging techniques. A total knee arthroplasty (TKA) removed from a patient was reviewed. The extracted prosthesis...

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Autores principales: Lau, Lawrence Chun Man, Lee, Wayne Yuk Wai, Butler, Anthony P H, Chernoglazov, Alex I, Chung, Kwong Yin, Ho, Kevin Ki Wai, Grifth, James, Butler, Philip H, Yung, Patrick Shu Hang
Lenguaje:eng
Publicado: 2021
Materias:
Acceso en línea:https://dx.doi.org/10.1038/s41598-020-80463-2
http://cds.cern.ch/record/2812519
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author Lau, Lawrence Chun Man
Lee, Wayne Yuk Wai
Butler, Anthony P H
Chernoglazov, Alex I
Chung, Kwong Yin
Ho, Kevin Ki Wai
Grifth, James
Butler, Philip H
Yung, Patrick Shu Hang
author_facet Lau, Lawrence Chun Man
Lee, Wayne Yuk Wai
Butler, Anthony P H
Chernoglazov, Alex I
Chung, Kwong Yin
Ho, Kevin Ki Wai
Grifth, James
Butler, Philip H
Yung, Patrick Shu Hang
author_sort Lau, Lawrence Chun Man
collection CERN
description To determine whether state-of-the-art multi-energy spectral photon-counting computed tomography (MARS) can detect knee arthroplasty implant failure not detected by standard pre-operative imaging techniques. A total knee arthroplasty (TKA) removed from a patient was reviewed. The extracted prosthesis [NexGen Legacy Posterior Stabilized (LPS) TKA] was analyzed as were pre-operative imaging examination and compared with a MARS-CT examination obtained of the extracted TKA prosthesis. Radiographs, fuoroscopy, ultrasound and MRI preoperatively did not reveal the cause of the implant failure. MARS CT images of the extracted prosthesis clearly showed the presence of posteromedial polyethylene and tibial tray wear which is compatible with the clinical appearance of the extracted TKA. MARS can identify polyethylene insert and metallic tibial tray wear as a cause of TKA failure, that could not be identifed with on standard pre-operative imaging. Although clinical MARS CT system is still under development, this case does illustrate its potential clinical usefulness. This is the frst study to document how MARS CT imaging can detect orthopedic implant failure not detected by standard current imaging techniques. This system has a potential clinical application in orthopedic patients.
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publishDate 2021
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spelling cern-28125192022-06-17T19:10:49Zdoi:10.1038/s41598-020-80463-2http://cds.cern.ch/record/2812519engLau, Lawrence Chun ManLee, Wayne Yuk WaiButler, Anthony P HChernoglazov, Alex IChung, Kwong YinHo, Kevin Ki WaiGrifth, JamesButler, Philip HYung, Patrick Shu HangMulti-energy spectral photon-counting computed tomography (MARS) for detection of arthroplasty implant failurePhysics in GeneralTo determine whether state-of-the-art multi-energy spectral photon-counting computed tomography (MARS) can detect knee arthroplasty implant failure not detected by standard pre-operative imaging techniques. A total knee arthroplasty (TKA) removed from a patient was reviewed. The extracted prosthesis [NexGen Legacy Posterior Stabilized (LPS) TKA] was analyzed as were pre-operative imaging examination and compared with a MARS-CT examination obtained of the extracted TKA prosthesis. Radiographs, fuoroscopy, ultrasound and MRI preoperatively did not reveal the cause of the implant failure. MARS CT images of the extracted prosthesis clearly showed the presence of posteromedial polyethylene and tibial tray wear which is compatible with the clinical appearance of the extracted TKA. MARS can identify polyethylene insert and metallic tibial tray wear as a cause of TKA failure, that could not be identifed with on standard pre-operative imaging. Although clinical MARS CT system is still under development, this case does illustrate its potential clinical usefulness. This is the frst study to document how MARS CT imaging can detect orthopedic implant failure not detected by standard current imaging techniques. This system has a potential clinical application in orthopedic patients.oai:cds.cern.ch:28125192021
spellingShingle Physics in General
Lau, Lawrence Chun Man
Lee, Wayne Yuk Wai
Butler, Anthony P H
Chernoglazov, Alex I
Chung, Kwong Yin
Ho, Kevin Ki Wai
Grifth, James
Butler, Philip H
Yung, Patrick Shu Hang
Multi-energy spectral photon-counting computed tomography (MARS) for detection of arthroplasty implant failure
title Multi-energy spectral photon-counting computed tomography (MARS) for detection of arthroplasty implant failure
title_full Multi-energy spectral photon-counting computed tomography (MARS) for detection of arthroplasty implant failure
title_fullStr Multi-energy spectral photon-counting computed tomography (MARS) for detection of arthroplasty implant failure
title_full_unstemmed Multi-energy spectral photon-counting computed tomography (MARS) for detection of arthroplasty implant failure
title_short Multi-energy spectral photon-counting computed tomography (MARS) for detection of arthroplasty implant failure
title_sort multi-energy spectral photon-counting computed tomography (mars) for detection of arthroplasty implant failure
topic Physics in General
url https://dx.doi.org/10.1038/s41598-020-80463-2
http://cds.cern.ch/record/2812519
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