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A COMPACT SYNCHROTRON FOR ADVANCED CANCER THERAPY WITH HELIUM AND PROTON BEAMS

Recent years have seen an increased interest in the use of helium for radiation therapy of cancer. Helium ions can be more precisely delivered to the tumour than protons or carbon ions, presently the only beams licensed for treatment, with a biological effectiveness between the two. The accelerator...

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Autores principales: Vretenar, Maurizio, Angoletta, Maria Elena, Bisoffi, Giovanni, Borburgh, Jan, Bottura, Luca, Palskis, Kristaps, Tranquille, Gerard Alain, Benedetto, Elena, Sapinski, Mariusz, Taylor, Rebecca Louise
Lenguaje:eng
Publicado: 2022
Materias:
Acceso en línea:http://cds.cern.ch/record/2813395
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author Vretenar, Maurizio
Angoletta, Maria Elena
Bisoffi, Giovanni
Borburgh, Jan
Bottura, Luca
Palskis, Kristaps
Tranquille, Gerard Alain
Benedetto, Elena
Sapinski, Mariusz
Taylor, Rebecca Louise
author_facet Vretenar, Maurizio
Angoletta, Maria Elena
Bisoffi, Giovanni
Borburgh, Jan
Bottura, Luca
Palskis, Kristaps
Tranquille, Gerard Alain
Benedetto, Elena
Sapinski, Mariusz
Taylor, Rebecca Louise
author_sort Vretenar, Maurizio
collection CERN
description Recent years have seen an increased interest in the use of helium for radiation therapy of cancer. Helium ions can be more precisely delivered to the tumour than protons or carbon ions, presently the only beams licensed for treatment, with a biological effectiveness between the two. The accelerator required for helium is considerably smaller than a standard carbon ion synchrotron. To exploit the potential of helium therapy and of other emerging particle therapy techniques, in the framework of the Next Ion Medical Machine Study (NIMMS) at CERN, the design of a compact synchrotron optimised for acceleration of proton and helium beams has been investigated. The synchrotron is based on a new magnet design, profits from a novel injector linac, and can provide both slow and fast extraction for conventional and FLASH therapy. Production of mini-beams, and operation with multiple ions for imaging and treatment are also considered. This accelerator is intended to become the main element of a facility devoted to a parallel programme of cancer research and treatment with proton and helium beams, to both cure patients and contribute to the assessment of helium beams as a new tool to fight cancer.
id cern-2813395
institution Organización Europea para la Investigación Nuclear
language eng
publishDate 2022
record_format invenio
spelling cern-28133952022-10-18T20:44:30Zhttp://cds.cern.ch/record/2813395engVretenar, MaurizioAngoletta, Maria ElenaBisoffi, GiovanniBorburgh, JanBottura, LucaPalskis, KristapsTranquille, Gerard AlainBenedetto, ElenaSapinski, MariuszTaylor, Rebecca LouiseA COMPACT SYNCHROTRON FOR ADVANCED CANCER THERAPY WITH HELIUM AND PROTON BEAMSAccelerators and Storage RingsRecent years have seen an increased interest in the use of helium for radiation therapy of cancer. Helium ions can be more precisely delivered to the tumour than protons or carbon ions, presently the only beams licensed for treatment, with a biological effectiveness between the two. The accelerator required for helium is considerably smaller than a standard carbon ion synchrotron. To exploit the potential of helium therapy and of other emerging particle therapy techniques, in the framework of the Next Ion Medical Machine Study (NIMMS) at CERN, the design of a compact synchrotron optimised for acceleration of proton and helium beams has been investigated. The synchrotron is based on a new magnet design, profits from a novel injector linac, and can provide both slow and fast extraction for conventional and FLASH therapy. Production of mini-beams, and operation with multiple ions for imaging and treatment are also considered. This accelerator is intended to become the main element of a facility devoted to a parallel programme of cancer research and treatment with proton and helium beams, to both cure patients and contribute to the assessment of helium beams as a new tool to fight cancer.CERN-ACC-NOTE-2022-0018CERN-ACC-NOTE-2022-018NIMMS-Note-010oai:cds.cern.ch:28133952022-06-01
spellingShingle Accelerators and Storage Rings
Vretenar, Maurizio
Angoletta, Maria Elena
Bisoffi, Giovanni
Borburgh, Jan
Bottura, Luca
Palskis, Kristaps
Tranquille, Gerard Alain
Benedetto, Elena
Sapinski, Mariusz
Taylor, Rebecca Louise
A COMPACT SYNCHROTRON FOR ADVANCED CANCER THERAPY WITH HELIUM AND PROTON BEAMS
title A COMPACT SYNCHROTRON FOR ADVANCED CANCER THERAPY WITH HELIUM AND PROTON BEAMS
title_full A COMPACT SYNCHROTRON FOR ADVANCED CANCER THERAPY WITH HELIUM AND PROTON BEAMS
title_fullStr A COMPACT SYNCHROTRON FOR ADVANCED CANCER THERAPY WITH HELIUM AND PROTON BEAMS
title_full_unstemmed A COMPACT SYNCHROTRON FOR ADVANCED CANCER THERAPY WITH HELIUM AND PROTON BEAMS
title_short A COMPACT SYNCHROTRON FOR ADVANCED CANCER THERAPY WITH HELIUM AND PROTON BEAMS
title_sort compact synchrotron for advanced cancer therapy with helium and proton beams
topic Accelerators and Storage Rings
url http://cds.cern.ch/record/2813395
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