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New Technologies for Time-of-Flight PET: Heterostructured Scintillators

<!--HTML-->Fiammetta Pagano1,2, Nicolaus Kratochwil1, Matteo Salomoni1, Loris Martinazzoli1,2, Marco Paganoni2,1, Marco Pizzichemi1,2, Etiennette Auffray1 1 European Organization for Nuclear Research (CERN). Geneva, Switzerland 2University of Milano-Bicocca. Piazza dell'Ateneo Nuovo, 1,...

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Autor principal: Pagano, Fiammetta
Lenguaje:eng
Publicado: 2022
Materias:
Acceso en línea:http://cds.cern.ch/record/2834130
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author Pagano, Fiammetta
author_facet Pagano, Fiammetta
author_sort Pagano, Fiammetta
collection CERN
description <!--HTML-->Fiammetta Pagano1,2, Nicolaus Kratochwil1, Matteo Salomoni1, Loris Martinazzoli1,2, Marco Paganoni2,1, Marco Pizzichemi1,2, Etiennette Auffray1 1 European Organization for Nuclear Research (CERN). Geneva, Switzerland 2University of Milano-Bicocca. Piazza dell'Ateneo Nuovo, 1, 20126 Milan, Italy Time-of-Flight (TOF) Positron Emission Tomography (PET) uses the time difference between the two annihilation photons to improve the Signal-to-Noise-Ration (SNR) compared to standard PET. A 10ps full-width-half-maximum (FWHM) coincidence time resolution (CTR) would mean a huge improvement in the SNR and spatial resolution, with an uncertainty of only 1.5mm. A CTR of 10ps would also increase effective sensitivity, which means earlier diagnosis and reduced patient exposure time to ionizing radiation, making this diagnostic test also possible for pregnant women and children. The aim of our KT/MA project is to develop TOF-PET modules toward 50ps time resolution based on heterostructure concept. Heterostructured scintillators rely on the combination of two materials with complementary properties (e.g., high stopping power and ultra-fast scintillation kinetics) to take advantage from both. In this talk, we show the validity of these approach and the investigation of the fundamental properties of these structures.
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institution Organización Europea para la Investigación Nuclear
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spelling cern-28341302022-11-02T22:03:24Zhttp://cds.cern.ch/record/2834130engPagano, FiammettaNew Technologies for Time-of-Flight PET: Heterostructured ScintillatorsEARLY-CAREER RESEARCHERS IN MEDICAL APPLICATIONS @ CERN – SHORT TALKSKT Seminars<!--HTML-->Fiammetta Pagano1,2, Nicolaus Kratochwil1, Matteo Salomoni1, Loris Martinazzoli1,2, Marco Paganoni2,1, Marco Pizzichemi1,2, Etiennette Auffray1 1 European Organization for Nuclear Research (CERN). Geneva, Switzerland 2University of Milano-Bicocca. Piazza dell'Ateneo Nuovo, 1, 20126 Milan, Italy Time-of-Flight (TOF) Positron Emission Tomography (PET) uses the time difference between the two annihilation photons to improve the Signal-to-Noise-Ration (SNR) compared to standard PET. A 10ps full-width-half-maximum (FWHM) coincidence time resolution (CTR) would mean a huge improvement in the SNR and spatial resolution, with an uncertainty of only 1.5mm. A CTR of 10ps would also increase effective sensitivity, which means earlier diagnosis and reduced patient exposure time to ionizing radiation, making this diagnostic test also possible for pregnant women and children. The aim of our KT/MA project is to develop TOF-PET modules toward 50ps time resolution based on heterostructure concept. Heterostructured scintillators rely on the combination of two materials with complementary properties (e.g., high stopping power and ultra-fast scintillation kinetics) to take advantage from both. In this talk, we show the validity of these approach and the investigation of the fundamental properties of these structures.oai:cds.cern.ch:28341302022
spellingShingle KT Seminars
Pagano, Fiammetta
New Technologies for Time-of-Flight PET: Heterostructured Scintillators
title New Technologies for Time-of-Flight PET: Heterostructured Scintillators
title_full New Technologies for Time-of-Flight PET: Heterostructured Scintillators
title_fullStr New Technologies for Time-of-Flight PET: Heterostructured Scintillators
title_full_unstemmed New Technologies for Time-of-Flight PET: Heterostructured Scintillators
title_short New Technologies for Time-of-Flight PET: Heterostructured Scintillators
title_sort new technologies for time-of-flight pet: heterostructured scintillators
topic KT Seminars
url http://cds.cern.ch/record/2834130
work_keys_str_mv AT paganofiammetta newtechnologiesfortimeofflightpetheterostructuredscintillators
AT paganofiammetta earlycareerresearchersinmedicalapplicationscernshorttalks