Cargando…

Half-life determination of $^{155}$Tb from mass-separated samples produced at CERN-MEDICIS

Terbium-155 has been identified for its potential for single-photon emission computed tomography (SPECT) in nuclear medicine. For activity measurements, an accurate and precise half-life of this radionuclide is required. However, the currently evaluated half-life of 5.32(6) d with a relative standar...

Descripción completa

Detalles Bibliográficos
Autores principales: Collins, S M, Robinson, A P, Ivanov, P, Köster, U, Cocolios, T E, Russell, B, Webster, B, Fenwick, A J, Duchemin, C, Ramos, J P, Chevallay, E, Jakobsson, U, Stegemann, S, Regan, P H, Stora, T
Lenguaje:eng
Publicado: 2022
Acceso en línea:https://dx.doi.org/10.1016/j.apradiso.2022.110480
http://cds.cern.ch/record/2837180
_version_ 1780975784724267008
author Collins, S M
Robinson, A P
Ivanov, P
Köster, U
Cocolios, T E
Russell, B
Webster, B
Fenwick, A J
Duchemin, C
Ramos, J P
Chevallay, E
Jakobsson, U
Stegemann, S
Regan, P H
Stora, T
author_facet Collins, S M
Robinson, A P
Ivanov, P
Köster, U
Cocolios, T E
Russell, B
Webster, B
Fenwick, A J
Duchemin, C
Ramos, J P
Chevallay, E
Jakobsson, U
Stegemann, S
Regan, P H
Stora, T
author_sort Collins, S M
collection CERN
description Terbium-155 has been identified for its potential for single-photon emission computed tomography (SPECT) in nuclear medicine. For activity measurements, an accurate and precise half-life of this radionuclide is required. However, the currently evaluated half-life of 5.32(6) d with a relative standard uncertainty of 1.1% determines the precision possible. Limited literature for the half-life measurements of this radionuclide is available and all reported investigations are prior to 1970. Further measurements are therefore needed to confirm the accuracy and improve the precision of the half-life for its use in the clinical setting. Two samples produced and mass separated at the CERN-MEDICIS facility have been measured at the National Physical Laboratory by two independent techniques: liquid scintillation counting and high-purity germanium gamma-ray spectrometry. A half-life of 5.2346(36) d has been determined from the weighted mean of the half-lives determined by the two techniques. The half-life reported in this work has shown a relative difference of 1.6% to the currently evaluated half-life and has vastly improved the precision. •Mass separated and radiochemically purified samples used to determine the half-life.•A half-life of 5.2346(36) d has been determined from two independent techniques.•A relative deviation of 1.6% from current evaluated half-life observed.•An order of magnitude increase in the precision has been achieved.
id cern-2837180
institution Organización Europea para la Investigación Nuclear
language eng
publishDate 2022
record_format invenio
spelling cern-28371802022-10-18T20:44:41Zdoi:10.1016/j.apradiso.2022.110480http://cds.cern.ch/record/2837180engCollins, S MRobinson, A PIvanov, PKöster, UCocolios, T ERussell, BWebster, BFenwick, A JDuchemin, CRamos, J PChevallay, EJakobsson, UStegemann, SRegan, P HStora, THalf-life determination of $^{155}$Tb from mass-separated samples produced at CERN-MEDICISTerbium-155 has been identified for its potential for single-photon emission computed tomography (SPECT) in nuclear medicine. For activity measurements, an accurate and precise half-life of this radionuclide is required. However, the currently evaluated half-life of 5.32(6) d with a relative standard uncertainty of 1.1% determines the precision possible. Limited literature for the half-life measurements of this radionuclide is available and all reported investigations are prior to 1970. Further measurements are therefore needed to confirm the accuracy and improve the precision of the half-life for its use in the clinical setting. Two samples produced and mass separated at the CERN-MEDICIS facility have been measured at the National Physical Laboratory by two independent techniques: liquid scintillation counting and high-purity germanium gamma-ray spectrometry. A half-life of 5.2346(36) d has been determined from the weighted mean of the half-lives determined by the two techniques. The half-life reported in this work has shown a relative difference of 1.6% to the currently evaluated half-life and has vastly improved the precision. •Mass separated and radiochemically purified samples used to determine the half-life.•A half-life of 5.2346(36) d has been determined from two independent techniques.•A relative deviation of 1.6% from current evaluated half-life observed.•An order of magnitude increase in the precision has been achieved.oai:cds.cern.ch:28371802022
spellingShingle Collins, S M
Robinson, A P
Ivanov, P
Köster, U
Cocolios, T E
Russell, B
Webster, B
Fenwick, A J
Duchemin, C
Ramos, J P
Chevallay, E
Jakobsson, U
Stegemann, S
Regan, P H
Stora, T
Half-life determination of $^{155}$Tb from mass-separated samples produced at CERN-MEDICIS
title Half-life determination of $^{155}$Tb from mass-separated samples produced at CERN-MEDICIS
title_full Half-life determination of $^{155}$Tb from mass-separated samples produced at CERN-MEDICIS
title_fullStr Half-life determination of $^{155}$Tb from mass-separated samples produced at CERN-MEDICIS
title_full_unstemmed Half-life determination of $^{155}$Tb from mass-separated samples produced at CERN-MEDICIS
title_short Half-life determination of $^{155}$Tb from mass-separated samples produced at CERN-MEDICIS
title_sort half-life determination of $^{155}$tb from mass-separated samples produced at cern-medicis
url https://dx.doi.org/10.1016/j.apradiso.2022.110480
http://cds.cern.ch/record/2837180
work_keys_str_mv AT collinssm halflifedeterminationof155tbfrommassseparatedsamplesproducedatcernmedicis
AT robinsonap halflifedeterminationof155tbfrommassseparatedsamplesproducedatcernmedicis
AT ivanovp halflifedeterminationof155tbfrommassseparatedsamplesproducedatcernmedicis
AT kosteru halflifedeterminationof155tbfrommassseparatedsamplesproducedatcernmedicis
AT cocolioste halflifedeterminationof155tbfrommassseparatedsamplesproducedatcernmedicis
AT russellb halflifedeterminationof155tbfrommassseparatedsamplesproducedatcernmedicis
AT websterb halflifedeterminationof155tbfrommassseparatedsamplesproducedatcernmedicis
AT fenwickaj halflifedeterminationof155tbfrommassseparatedsamplesproducedatcernmedicis
AT ducheminc halflifedeterminationof155tbfrommassseparatedsamplesproducedatcernmedicis
AT ramosjp halflifedeterminationof155tbfrommassseparatedsamplesproducedatcernmedicis
AT chevallaye halflifedeterminationof155tbfrommassseparatedsamplesproducedatcernmedicis
AT jakobssonu halflifedeterminationof155tbfrommassseparatedsamplesproducedatcernmedicis
AT stegemanns halflifedeterminationof155tbfrommassseparatedsamplesproducedatcernmedicis
AT reganph halflifedeterminationof155tbfrommassseparatedsamplesproducedatcernmedicis
AT storat halflifedeterminationof155tbfrommassseparatedsamplesproducedatcernmedicis