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A Thermal Sublimation Generator of $^{131 \textrm{m}}$Xe
Stable and unstable isotopes of the heavy noble gas xenon find use in various medical applications. However, apart from $^{133}$Xe, used for Single Photon Emission Computed Tomography, radioactive isotopes of xenon are currently complicated to obtain in small quantities. With the GAMMA-MRI project...
Autores principales: | , , , , , , , , |
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Lenguaje: | eng |
Publicado: |
2022
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Materias: | |
Acceso en línea: | https://dx.doi.org/10.3390/instruments6040076 http://cds.cern.ch/record/2845023 |
Sumario: | Stable and unstable isotopes of the heavy noble gas xenon find use in various medical
applications. However, apart from $^{133}$Xe, used for Single Photon Emission Computed Tomography,
radioactive isotopes of xenon are currently complicated to obtain in small quantities. With the
GAMMA-MRI project in mind, we investigated a thermal sublimation generator of the long-lived excited state (isomer) $^{131 \textrm{m}}$Xe. This production method utilized the decay of $^{131}$I, obtained commercially
from a hospital supplier in the form of Na131I powder. Heat treatments of the Na $^{131}$I powder and cryogenic trapping of released $^{131 \textrm{m}}$Xe allowed us to collect up to 88% of the produced xenon. Our method
provides an isomeric mixture of $^{131 \textrm{m}}$Xe and $^{131}$Xe. With improvements in scalability and chemical
purification, this method could be a cost-effective source of $^{131 \textrm{m}}$Xe for small-scale experiments. |
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