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A Thermal Sublimation Generator of $^{131 \textrm{m}}$Xe

Stable and unstable isotopes of the heavy noble gas xenon find use in various medical applications. However, apart from  $^{133}$Xe, used for Single Photon Emission Computed Tomography, radioactive isotopes of xenon are currently complicated to obtain in small quantities. With the GAMMA-MRI project...

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Autores principales: Kulesz, Karolina, Azaryan, Nikolay, Baranowski, Mikołaj, Chojnacki, Mateusz Jerzy, Köster, Ulli, Lica, Razvan, Pascu, Sorin Gabriel, Jolivet, Renaud Blaise, Kowalska, Magdalena
Lenguaje:eng
Publicado: 2022
Materias:
Acceso en línea:https://dx.doi.org/10.3390/instruments6040076
http://cds.cern.ch/record/2845023
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author Kulesz, Karolina
Azaryan, Nikolay
Baranowski, Mikołaj
Chojnacki, Mateusz Jerzy
Köster, Ulli
Lica, Razvan
Pascu, Sorin Gabriel
Jolivet, Renaud Blaise
Kowalska, Magdalena
author_facet Kulesz, Karolina
Azaryan, Nikolay
Baranowski, Mikołaj
Chojnacki, Mateusz Jerzy
Köster, Ulli
Lica, Razvan
Pascu, Sorin Gabriel
Jolivet, Renaud Blaise
Kowalska, Magdalena
author_sort Kulesz, Karolina
collection CERN
description Stable and unstable isotopes of the heavy noble gas xenon find use in various medical applications. However, apart from  $^{133}$Xe, used for Single Photon Emission Computed Tomography, radioactive isotopes of xenon are currently complicated to obtain in small quantities. With the GAMMA-MRI project in mind, we investigated a thermal sublimation generator of the long-lived excited state (isomer) $^{131 \textrm{m}}$Xe. This production method utilized the decay of $^{131}$I, obtained commercially from a hospital supplier in the form of Na131I powder. Heat treatments of the Na $^{131}$I powder and cryogenic trapping of released $^{131 \textrm{m}}$Xe allowed us to collect up to 88% of the produced xenon. Our method provides an isomeric mixture of $^{131 \textrm{m}}$Xe and  $^{131}$Xe. With improvements in scalability and chemical purification, this method could be a cost-effective source of $^{131 \textrm{m}}$Xe for small-scale experiments.
id cern-2845023
institution Organización Europea para la Investigación Nuclear
language eng
publishDate 2022
record_format invenio
spelling cern-28450232023-03-31T10:13:01Zdoi:10.3390/instruments6040076http://cds.cern.ch/record/2845023engKulesz, KarolinaAzaryan, NikolayBaranowski, MikołajChojnacki, Mateusz JerzyKöster, UlliLica, RazvanPascu, Sorin GabrielJolivet, Renaud BlaiseKowalska, MagdalenaA Thermal Sublimation Generator of $^{131 \textrm{m}}$XeDetectors and Experimental TechniquesStable and unstable isotopes of the heavy noble gas xenon find use in various medical applications. However, apart from  $^{133}$Xe, used for Single Photon Emission Computed Tomography, radioactive isotopes of xenon are currently complicated to obtain in small quantities. With the GAMMA-MRI project in mind, we investigated a thermal sublimation generator of the long-lived excited state (isomer) $^{131 \textrm{m}}$Xe. This production method utilized the decay of $^{131}$I, obtained commercially from a hospital supplier in the form of Na131I powder. Heat treatments of the Na $^{131}$I powder and cryogenic trapping of released $^{131 \textrm{m}}$Xe allowed us to collect up to 88% of the produced xenon. Our method provides an isomeric mixture of $^{131 \textrm{m}}$Xe and  $^{131}$Xe. With improvements in scalability and chemical purification, this method could be a cost-effective source of $^{131 \textrm{m}}$Xe for small-scale experiments.oai:cds.cern.ch:28450232022
spellingShingle Detectors and Experimental Techniques
Kulesz, Karolina
Azaryan, Nikolay
Baranowski, Mikołaj
Chojnacki, Mateusz Jerzy
Köster, Ulli
Lica, Razvan
Pascu, Sorin Gabriel
Jolivet, Renaud Blaise
Kowalska, Magdalena
A Thermal Sublimation Generator of $^{131 \textrm{m}}$Xe
title A Thermal Sublimation Generator of $^{131 \textrm{m}}$Xe
title_full A Thermal Sublimation Generator of $^{131 \textrm{m}}$Xe
title_fullStr A Thermal Sublimation Generator of $^{131 \textrm{m}}$Xe
title_full_unstemmed A Thermal Sublimation Generator of $^{131 \textrm{m}}$Xe
title_short A Thermal Sublimation Generator of $^{131 \textrm{m}}$Xe
title_sort thermal sublimation generator of $^{131 \textrm{m}}$xe
topic Detectors and Experimental Techniques
url https://dx.doi.org/10.3390/instruments6040076
http://cds.cern.ch/record/2845023
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