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A Thermal Sublimation Generator of $^{131 \textrm{m}}$Xe
Stable and unstable isotopes of the heavy noble gas xenon find use in various medical applications. However, apart from $^{133}$Xe, used for Single Photon Emission Computed Tomography, radioactive isotopes of xenon are currently complicated to obtain in small quantities. With the GAMMA-MRI project...
Autores principales: | , , , , , , , , |
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Lenguaje: | eng |
Publicado: |
2022
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Acceso en línea: | https://dx.doi.org/10.3390/instruments6040076 http://cds.cern.ch/record/2845023 |
_version_ | 1780976516867293184 |
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author | Kulesz, Karolina Azaryan, Nikolay Baranowski, Mikołaj Chojnacki, Mateusz Jerzy Köster, Ulli Lica, Razvan Pascu, Sorin Gabriel Jolivet, Renaud Blaise Kowalska, Magdalena |
author_facet | Kulesz, Karolina Azaryan, Nikolay Baranowski, Mikołaj Chojnacki, Mateusz Jerzy Köster, Ulli Lica, Razvan Pascu, Sorin Gabriel Jolivet, Renaud Blaise Kowalska, Magdalena |
author_sort | Kulesz, Karolina |
collection | CERN |
description | Stable and unstable isotopes of the heavy noble gas xenon find use in various medical
applications. However, apart from $^{133}$Xe, used for Single Photon Emission Computed Tomography,
radioactive isotopes of xenon are currently complicated to obtain in small quantities. With the
GAMMA-MRI project in mind, we investigated a thermal sublimation generator of the long-lived excited state (isomer) $^{131 \textrm{m}}$Xe. This production method utilized the decay of $^{131}$I, obtained commercially
from a hospital supplier in the form of Na131I powder. Heat treatments of the Na $^{131}$I powder and cryogenic trapping of released $^{131 \textrm{m}}$Xe allowed us to collect up to 88% of the produced xenon. Our method
provides an isomeric mixture of $^{131 \textrm{m}}$Xe and $^{131}$Xe. With improvements in scalability and chemical
purification, this method could be a cost-effective source of $^{131 \textrm{m}}$Xe for small-scale experiments. |
id | cern-2845023 |
institution | Organización Europea para la Investigación Nuclear |
language | eng |
publishDate | 2022 |
record_format | invenio |
spelling | cern-28450232023-03-31T10:13:01Zdoi:10.3390/instruments6040076http://cds.cern.ch/record/2845023engKulesz, KarolinaAzaryan, NikolayBaranowski, MikołajChojnacki, Mateusz JerzyKöster, UlliLica, RazvanPascu, Sorin GabrielJolivet, Renaud BlaiseKowalska, MagdalenaA Thermal Sublimation Generator of $^{131 \textrm{m}}$XeDetectors and Experimental TechniquesStable and unstable isotopes of the heavy noble gas xenon find use in various medical applications. However, apart from $^{133}$Xe, used for Single Photon Emission Computed Tomography, radioactive isotopes of xenon are currently complicated to obtain in small quantities. With the GAMMA-MRI project in mind, we investigated a thermal sublimation generator of the long-lived excited state (isomer) $^{131 \textrm{m}}$Xe. This production method utilized the decay of $^{131}$I, obtained commercially from a hospital supplier in the form of Na131I powder. Heat treatments of the Na $^{131}$I powder and cryogenic trapping of released $^{131 \textrm{m}}$Xe allowed us to collect up to 88% of the produced xenon. Our method provides an isomeric mixture of $^{131 \textrm{m}}$Xe and $^{131}$Xe. With improvements in scalability and chemical purification, this method could be a cost-effective source of $^{131 \textrm{m}}$Xe for small-scale experiments.oai:cds.cern.ch:28450232022 |
spellingShingle | Detectors and Experimental Techniques Kulesz, Karolina Azaryan, Nikolay Baranowski, Mikołaj Chojnacki, Mateusz Jerzy Köster, Ulli Lica, Razvan Pascu, Sorin Gabriel Jolivet, Renaud Blaise Kowalska, Magdalena A Thermal Sublimation Generator of $^{131 \textrm{m}}$Xe |
title | A Thermal Sublimation Generator of $^{131 \textrm{m}}$Xe |
title_full | A Thermal Sublimation Generator of $^{131 \textrm{m}}$Xe |
title_fullStr | A Thermal Sublimation Generator of $^{131 \textrm{m}}$Xe |
title_full_unstemmed | A Thermal Sublimation Generator of $^{131 \textrm{m}}$Xe |
title_short | A Thermal Sublimation Generator of $^{131 \textrm{m}}$Xe |
title_sort | thermal sublimation generator of $^{131 \textrm{m}}$xe |
topic | Detectors and Experimental Techniques |
url | https://dx.doi.org/10.3390/instruments6040076 http://cds.cern.ch/record/2845023 |
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