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A Compact Synchrotron for Advanced Cancer Therapy with Helium and Proton Beams

Recent years have seen an increased interest in the use of helium for radiation therapy of cancer. Helium ions can be more precisely delivered to the tumour than protons or carbon ions, presently the only beams licensed for treatment, with a biological effectiveness between the two. The accelerator...

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Autores principales: Vretenar, Maurizio, Angoletta, Maria Elena, Benedetto, Elena, Bisoffi, Giovanni, Borburgh, Jan, Bottura, Luca, Paļskis, Kristaps, Sapinski, Mariusz, Taylor, Rebecca, Tranquille, Gerard
Lenguaje:eng
Publicado: 2022
Materias:
Acceso en línea:https://dx.doi.org/10.18429/JACoW-IPAC2022-TUOZGD2
http://cds.cern.ch/record/2845756
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author Vretenar, Maurizio
Angoletta, Maria Elena
Benedetto, Elena
Bisoffi, Giovanni
Borburgh, Jan
Bottura, Luca
Paļskis, Kristaps
Sapinski, Mariusz
Taylor, Rebecca
Tranquille, Gerard
author_facet Vretenar, Maurizio
Angoletta, Maria Elena
Benedetto, Elena
Bisoffi, Giovanni
Borburgh, Jan
Bottura, Luca
Paļskis, Kristaps
Sapinski, Mariusz
Taylor, Rebecca
Tranquille, Gerard
author_sort Vretenar, Maurizio
collection CERN
description Recent years have seen an increased interest in the use of helium for radiation therapy of cancer. Helium ions can be more precisely delivered to the tumour than protons or carbon ions, presently the only beams licensed for treatment, with a biological effectiveness between the two. The accelerator required for helium is considerably smaller than a standard carbon ion synchrotron. To exploit the potential of helium therapy and of other emerging particle therapy techniques, in the framework of the Next Ion Medical Machine Study (NIMMS) at CERN the design of a compact synchrotron optimised for acceleration of proton and helium beams has been investigated. The synchrotron is based on a new magnet design, profits from a novel injector linac, and can provide both slow and fast extraction for conventional and FLASH therapy. Production of mini-beams, and operation with multiple ions for imaging and treatment are also considered. This accelerator is intended to become the main element of a facility devoted to a programme of cancer research and treatment with proton and helium beams, to both cure patients and contribute to the assessment of helium beams as a new tool to fight cancer.
id cern-2845756
institution Organización Europea para la Investigación Nuclear
language eng
publishDate 2022
record_format invenio
spelling cern-28457562023-01-11T21:31:17Zdoi:10.18429/JACoW-IPAC2022-TUOZGD2http://cds.cern.ch/record/2845756engVretenar, MaurizioAngoletta, Maria ElenaBenedetto, ElenaBisoffi, GiovanniBorburgh, JanBottura, LucaPaļskis, KristapsSapinski, MariuszTaylor, RebeccaTranquille, GerardA Compact Synchrotron for Advanced Cancer Therapy with Helium and Proton BeamsAccelerators and Storage RingsRecent years have seen an increased interest in the use of helium for radiation therapy of cancer. Helium ions can be more precisely delivered to the tumour than protons or carbon ions, presently the only beams licensed for treatment, with a biological effectiveness between the two. The accelerator required for helium is considerably smaller than a standard carbon ion synchrotron. To exploit the potential of helium therapy and of other emerging particle therapy techniques, in the framework of the Next Ion Medical Machine Study (NIMMS) at CERN the design of a compact synchrotron optimised for acceleration of proton and helium beams has been investigated. The synchrotron is based on a new magnet design, profits from a novel injector linac, and can provide both slow and fast extraction for conventional and FLASH therapy. Production of mini-beams, and operation with multiple ions for imaging and treatment are also considered. This accelerator is intended to become the main element of a facility devoted to a programme of cancer research and treatment with proton and helium beams, to both cure patients and contribute to the assessment of helium beams as a new tool to fight cancer.oai:cds.cern.ch:28457562022
spellingShingle Accelerators and Storage Rings
Vretenar, Maurizio
Angoletta, Maria Elena
Benedetto, Elena
Bisoffi, Giovanni
Borburgh, Jan
Bottura, Luca
Paļskis, Kristaps
Sapinski, Mariusz
Taylor, Rebecca
Tranquille, Gerard
A Compact Synchrotron for Advanced Cancer Therapy with Helium and Proton Beams
title A Compact Synchrotron for Advanced Cancer Therapy with Helium and Proton Beams
title_full A Compact Synchrotron for Advanced Cancer Therapy with Helium and Proton Beams
title_fullStr A Compact Synchrotron for Advanced Cancer Therapy with Helium and Proton Beams
title_full_unstemmed A Compact Synchrotron for Advanced Cancer Therapy with Helium and Proton Beams
title_short A Compact Synchrotron for Advanced Cancer Therapy with Helium and Proton Beams
title_sort compact synchrotron for advanced cancer therapy with helium and proton beams
topic Accelerators and Storage Rings
url https://dx.doi.org/10.18429/JACoW-IPAC2022-TUOZGD2
http://cds.cern.ch/record/2845756
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