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VHEE High Dose Rate Dosimetry Studies in CLEAR

The 200 MeV electron beam of the CERN Linear Accelerator for Research (CLEAR) user facility at CERN has been intensively used to study the potential use of Very High Energy Electrons (VHEE) in cancer radiotherapy. In particular, irradiation tests have been performed in the high dose rate regime, whi...

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Autores principales: Rieker, Vilde, Bateman, Joseph, Corsini, Roberto, Dyks, Luke, Farabolini, Wilfrid, Korysko, Pierre
Lenguaje:eng
Publicado: 2022
Materias:
Acceso en línea:https://dx.doi.org/10.18429/JACoW-IPAC2022-THPOMS031
http://cds.cern.ch/record/2845882
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author Rieker, Vilde
Bateman, Joseph
Corsini, Roberto
Dyks, Luke
Farabolini, Wilfrid
Korysko, Pierre
author_facet Rieker, Vilde
Bateman, Joseph
Corsini, Roberto
Dyks, Luke
Farabolini, Wilfrid
Korysko, Pierre
author_sort Rieker, Vilde
collection CERN
description The 200 MeV electron beam of the CERN Linear Accelerator for Research (CLEAR) user facility at CERN has been intensively used to study the potential use of Very High Energy Electrons (VHEE) in cancer radiotherapy. In particular, irradiation tests have been performed in the high dose rate regime, which has gained a lot of interest for the so called FLASH biological effect, in which cancer cells are damaged while healthy tissue is largely spared. High dose rate dosimetry, though, poses a number of challenges: to validate standard or new methods of passive dosimetry, like radiochromic films and alanine pellets, and especially to develop new methods for real-time dosimetry since the normally used ionization chambers suffer from non-linear effects at high dose rates. In this paper we describe the results of experimental activities at CLEAR aimed at developing solid, high-dose rate dosimetry standards adapted to VHEE beams.
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institution Organización Europea para la Investigación Nuclear
language eng
publishDate 2022
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spelling cern-28458822023-01-11T21:31:29Zdoi:10.18429/JACoW-IPAC2022-THPOMS031http://cds.cern.ch/record/2845882engRieker, VildeBateman, JosephCorsini, RobertoDyks, LukeFarabolini, WilfridKorysko, PierreVHEE High Dose Rate Dosimetry Studies in CLEARAccelerators and Storage RingsThe 200 MeV electron beam of the CERN Linear Accelerator for Research (CLEAR) user facility at CERN has been intensively used to study the potential use of Very High Energy Electrons (VHEE) in cancer radiotherapy. In particular, irradiation tests have been performed in the high dose rate regime, which has gained a lot of interest for the so called FLASH biological effect, in which cancer cells are damaged while healthy tissue is largely spared. High dose rate dosimetry, though, poses a number of challenges: to validate standard or new methods of passive dosimetry, like radiochromic films and alanine pellets, and especially to develop new methods for real-time dosimetry since the normally used ionization chambers suffer from non-linear effects at high dose rates. In this paper we describe the results of experimental activities at CLEAR aimed at developing solid, high-dose rate dosimetry standards adapted to VHEE beams.oai:cds.cern.ch:28458822022
spellingShingle Accelerators and Storage Rings
Rieker, Vilde
Bateman, Joseph
Corsini, Roberto
Dyks, Luke
Farabolini, Wilfrid
Korysko, Pierre
VHEE High Dose Rate Dosimetry Studies in CLEAR
title VHEE High Dose Rate Dosimetry Studies in CLEAR
title_full VHEE High Dose Rate Dosimetry Studies in CLEAR
title_fullStr VHEE High Dose Rate Dosimetry Studies in CLEAR
title_full_unstemmed VHEE High Dose Rate Dosimetry Studies in CLEAR
title_short VHEE High Dose Rate Dosimetry Studies in CLEAR
title_sort vhee high dose rate dosimetry studies in clear
topic Accelerators and Storage Rings
url https://dx.doi.org/10.18429/JACoW-IPAC2022-THPOMS031
http://cds.cern.ch/record/2845882
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AT corsiniroberto vheehighdoseratedosimetrystudiesinclear
AT dyksluke vheehighdoseratedosimetrystudiesinclear
AT faraboliniwilfrid vheehighdoseratedosimetrystudiesinclear
AT koryskopierre vheehighdoseratedosimetrystudiesinclear