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Direct Observation of Nanosecond Water Exchange Dynamics at a Protein Metal Site
Nanosecond ligand exchange dynamics at metal sites within proteins is essential in catalysis, metal ion transport, and regulatory metallobiochemistry. Herein we present direct observation of the exchange dynamics of water at a $Cd^{2+}$ binding site within two de novo designed metalloprotein constru...
| Autores principales: | , , , , , |
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| Lenguaje: | eng |
| Publicado: |
2017
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| Materias: | |
| Acceso en línea: | https://dx.doi.org/10.1021/jacs.6b11525 http://cds.cern.ch/record/2270578 |