Challenges in the modeling of nuclear reactions for theranostic applications

We present the results obtained for a selection of nuclear reactions of interest for the INFN SPES/LARAMED initiative, focusing on the study of cross sections for the production of theranostic 47 Sc from Ti and V targets with state-of-art nuclear codes (Talys, Empire and Fluka). Radioisotope product...

Descripción completa

Detalles Bibliográficos
Autores principales: A , Fontana, S , Calzaferri, L , Canton, J , Esposito, L , Mou, G , Pupillo, Rossi Alvarez, C
Lenguaje:eng
Publicado: CERN 2019
Materias:
Other
Acceso en línea:http://cds.cern.ch/record/2669510
_version_ 1780962340586389504
author A , Fontana
S , Calzaferri
L , Canton
J , Esposito
L , Mou
G , Pupillo
Rossi Alvarez, C
author_facet A , Fontana
S , Calzaferri
L , Canton
J , Esposito
L , Mou
G , Pupillo
Rossi Alvarez, C
author_sort A , Fontana
collection CERN
description We present the results obtained for a selection of nuclear reactions of interest for the INFN SPES/LARAMED initiative, focusing on the study of cross sections for the production of theranostic 47 Sc from Ti and V targets with state-of-art nuclear codes (Talys, Empire and Fluka). Radioisotope production for theranostics (i.e. their combined use for therapy and diagnostics) is currently a topic of great interest and a set of new, emerging isotopes has been identified to be used with existing clinical scanners or as therapeutic agents in alternative to the standard isotopes. Three new promising isotopes were recently recommended by IAEA: $^{67}$Cu, $^{47}$Sc and $^{186}$Re. These isotopes can be produced at cyclotrons by means of nuclear reactions induced by charged particles: however these processes produce the desired nuclide together with other contaminants , and require further purification of the samples before their medical use. High-purity production is a difficult task and poses restrictions to the irradiation conditions in order to optimize the reactions yield.
id oai-inspirehep.net-1726669
institution Organización Europea para la Investigación Nuclear
language eng
publishDate 2019
publisher CERN
record_format invenio
spelling oai-inspirehep.net-17266692019-09-30T06:29:59Zhttp://cds.cern.ch/record/2669510engA , FontanaS , CalzaferriL , CantonJ , EspositoL , MouG , PupilloRossi Alvarez, CChallenges in the modeling of nuclear reactions for theranostic applicationsOtherWe present the results obtained for a selection of nuclear reactions of interest for the INFN SPES/LARAMED initiative, focusing on the study of cross sections for the production of theranostic 47 Sc from Ti and V targets with state-of-art nuclear codes (Talys, Empire and Fluka). Radioisotope production for theranostics (i.e. their combined use for therapy and diagnostics) is currently a topic of great interest and a set of new, emerging isotopes has been identified to be used with existing clinical scanners or as therapeutic agents in alternative to the standard isotopes. Three new promising isotopes were recently recommended by IAEA: $^{67}$Cu, $^{47}$Sc and $^{186}$Re. These isotopes can be produced at cyclotrons by means of nuclear reactions induced by charged particles: however these processes produce the desired nuclide together with other contaminants , and require further purification of the samples before their medical use. High-purity production is a difficult task and poses restrictions to the irradiation conditions in order to optimize the reactions yield.CERNoai:inspirehep.net:17266692019
spellingShingle Other
A , Fontana
S , Calzaferri
L , Canton
J , Esposito
L , Mou
G , Pupillo
Rossi Alvarez, C
Challenges in the modeling of nuclear reactions for theranostic applications
title Challenges in the modeling of nuclear reactions for theranostic applications
title_full Challenges in the modeling of nuclear reactions for theranostic applications
title_fullStr Challenges in the modeling of nuclear reactions for theranostic applications
title_full_unstemmed Challenges in the modeling of nuclear reactions for theranostic applications
title_short Challenges in the modeling of nuclear reactions for theranostic applications
title_sort challenges in the modeling of nuclear reactions for theranostic applications
topic Other
url http://cds.cern.ch/record/2669510
work_keys_str_mv AT afontana challengesinthemodelingofnuclearreactionsfortheranosticapplications
AT scalzaferri challengesinthemodelingofnuclearreactionsfortheranosticapplications
AT lcanton challengesinthemodelingofnuclearreactionsfortheranosticapplications
AT jesposito challengesinthemodelingofnuclearreactionsfortheranosticapplications
AT lmou challengesinthemodelingofnuclearreactionsfortheranosticapplications
AT gpupillo challengesinthemodelingofnuclearreactionsfortheranosticapplications
AT rossialvarezc challengesinthemodelingofnuclearreactionsfortheranosticapplications

Ejemplares similares