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Sumario:The fourth one-month Pb-Pb collision run brought LHC Run 2 to an end in December 2018. Following the tendency to reduce dependence on the configuration of the preceding proton run, a completely new optics cycle with the strongest ever focussing at the ALICE and LHCb experiments was designed and rapidly implemented, demonstrating the maturity of the collider’s operating modes. Beam-loss monitor thresholds were carefully adjusted to provide optimal protection from the multiple loss mechanisms in heavy-ion operation. A switch from a basic bunch-spacing of 100 ns to 75 ns was made as the beam became available from the injector chain. A new record luminosity, 6 times the original design and close to the operating value proposed for HL-LHC, provided validation of the strategy for mitigating quenches due to bound-free pair production (BFPP) at the interaction points of the ATLAS and CMS experiments. Most of the beam parameters of the HL-LHC Pb-Pb upgrade were attained during this run and the integrated luminosity goals for the first 10 years of LHC operation were substantially exceeded.