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Preclinical investigations and first-in-human application of $^{152}$Tb-PSMA-617 for PET/CT imaging of prostate cancer
The results of this study demonstrate the successful preparation and preclinical testing of $^{152}$Tb-PSMA-617 and its first application in a patient with mCRPC. This work could pave the way towards clinical application of other Tb radionuclides in the near future, most importantly $^{161}$Tb, whic...
| Autores principales: | , , , , , , , , , , , , |
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| Lenguaje: | eng |
| Publicado: |
2019
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| Materias: | |
| Acceso en línea: | https://dx.doi.org/10.1186/s13550-019-0538-1 http://cds.cern.ch/record/2690552 |
| _version_ | 1780963831936188416 |
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| author | Müller, Cristina Singh, Aviral Umbricht, Christoph A Kulkarni, Harshad R Johnston, Karl Benešová, Martina Senftleben, Stefan Müller, Dirk Vermeulen, Christiaan Schibli, Roger Köster, Ulli van der Meulen, Nicholas P Baum, Richard P |
| author_facet | Müller, Cristina Singh, Aviral Umbricht, Christoph A Kulkarni, Harshad R Johnston, Karl Benešová, Martina Senftleben, Stefan Müller, Dirk Vermeulen, Christiaan Schibli, Roger Köster, Ulli van der Meulen, Nicholas P Baum, Richard P |
| author_sort | Müller, Cristina |
| collection | CERN |
| description | The results of this study demonstrate the successful preparation and preclinical testing of $^{152}$Tb-PSMA-617 and its first application in a patient with mCRPC. This work could pave the way towards clinical application of other Tb radionuclides in the near future, most importantly $^{161}$Tb, which has promising decay characteristics for an effective treatment of mCRPC patients. |
| id | oai-inspirehep.net-1753803 |
| institution | Organización Europea para la Investigación Nuclear |
| language | eng |
| publishDate | 2019 |
| record_format | invenio |
| spelling | oai-inspirehep.net-17538032022-08-10T12:25:41Zdoi:10.1186/s13550-019-0538-1http://cds.cern.ch/record/2690552engMüller, CristinaSingh, AviralUmbricht, Christoph AKulkarni, Harshad RJohnston, KarlBenešová, MartinaSenftleben, StefanMüller, DirkVermeulen, ChristiaanSchibli, RogerKöster, Ullivan der Meulen, Nicholas PBaum, Richard PPreclinical investigations and first-in-human application of $^{152}$Tb-PSMA-617 for PET/CT imaging of prostate cancerOtherThe results of this study demonstrate the successful preparation and preclinical testing of $^{152}$Tb-PSMA-617 and its first application in a patient with mCRPC. This work could pave the way towards clinical application of other Tb radionuclides in the near future, most importantly $^{161}$Tb, which has promising decay characteristics for an effective treatment of mCRPC patients.oai:inspirehep.net:17538032019 |
| spellingShingle | Other Müller, Cristina Singh, Aviral Umbricht, Christoph A Kulkarni, Harshad R Johnston, Karl Benešová, Martina Senftleben, Stefan Müller, Dirk Vermeulen, Christiaan Schibli, Roger Köster, Ulli van der Meulen, Nicholas P Baum, Richard P Preclinical investigations and first-in-human application of $^{152}$Tb-PSMA-617 for PET/CT imaging of prostate cancer |
| title | Preclinical investigations and first-in-human application of $^{152}$Tb-PSMA-617 for PET/CT imaging of prostate cancer |
| title_full | Preclinical investigations and first-in-human application of $^{152}$Tb-PSMA-617 for PET/CT imaging of prostate cancer |
| title_fullStr | Preclinical investigations and first-in-human application of $^{152}$Tb-PSMA-617 for PET/CT imaging of prostate cancer |
| title_full_unstemmed | Preclinical investigations and first-in-human application of $^{152}$Tb-PSMA-617 for PET/CT imaging of prostate cancer |
| title_short | Preclinical investigations and first-in-human application of $^{152}$Tb-PSMA-617 for PET/CT imaging of prostate cancer |
| title_sort | preclinical investigations and first-in-human application of $^{152}$tb-psma-617 for pet/ct imaging of prostate cancer |
| topic | Other |
| url | https://dx.doi.org/10.1186/s13550-019-0538-1 http://cds.cern.ch/record/2690552 |
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