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Exploring neutron capture therapy with $^{33}$S and $^{10}$B
The $^{33}$S(n,α)$^{30}$Si reaction was proposed as cooperative neutron capturer to $^{10}$B(n,α)$^{7}$Li in Neutron Capture Therapy (NCT). At that moment, the available $^{33}$S(n,α)$^{30}$Si cross-section data were scarce and discrepant in key energy ranges for its use in NCT. Since then, three ex...
Autores principales: | , , , , |
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Lenguaje: | eng |
Publicado: |
2020
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Acceso en línea: | https://dx.doi.org/10.1016/j.apradiso.2020.109220 http://cds.cern.ch/record/2725884 |
Sumario: | The $^{33}$S(n,α)$^{30}$Si reaction was proposed as cooperative neutron capturer to $^{10}$B(n,α)$^{7}$Li in Neutron Capture Therapy (NCT). At that moment, the available $^{33}$S(n,α)$^{30}$Si cross-section data were scarce and discrepant in key energy ranges for its use in NCT. Since then, three experiments have been carried out at n_TOF facility at CERN and at Institut Laue-Langevin. These new data are used for the calculation of the dose rate on ICRU-4 tissue by using kerma factors, a simplified model of tissue and a 13.45 keV neutron beam, energy of the most important $^{33}$S(n,α)$^{30}$Si resonance. A significant enhancement of the dose rate due to the presence of $^{33}$S is shown. In spite of the limitations, the cooperative action of $^{33}$S and $^{10}$B is an interesting possibility to be studied for accelerator-based neutron sources with non-moderated neutrons. |
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