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Exploring neutron capture therapy with $^{33}$S and $^{10}$B
The $^{33}$S(n,α)$^{30}$Si reaction was proposed as cooperative neutron capturer to $^{10}$B(n,α)$^{7}$Li in Neutron Capture Therapy (NCT). At that moment, the available $^{33}$S(n,α)$^{30}$Si cross-section data were scarce and discrepant in key energy ranges for its use in NCT. Since then, three ex...
Autores principales: | , , , , |
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Lenguaje: | eng |
Publicado: |
2020
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Acceso en línea: | https://dx.doi.org/10.1016/j.apradiso.2020.109220 http://cds.cern.ch/record/2725884 |
_version_ | 1780966146971795456 |
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author | López-Casas, I Praena, J Arias de Saavedra, F Sabaté-Gilarte, M Porras, I |
author_facet | López-Casas, I Praena, J Arias de Saavedra, F Sabaté-Gilarte, M Porras, I |
author_sort | López-Casas, I |
collection | CERN |
description | The $^{33}$S(n,α)$^{30}$Si reaction was proposed as cooperative neutron capturer to $^{10}$B(n,α)$^{7}$Li in Neutron Capture Therapy (NCT). At that moment, the available $^{33}$S(n,α)$^{30}$Si cross-section data were scarce and discrepant in key energy ranges for its use in NCT. Since then, three experiments have been carried out at n_TOF facility at CERN and at Institut Laue-Langevin. These new data are used for the calculation of the dose rate on ICRU-4 tissue by using kerma factors, a simplified model of tissue and a 13.45 keV neutron beam, energy of the most important $^{33}$S(n,α)$^{30}$Si resonance. A significant enhancement of the dose rate due to the presence of $^{33}$S is shown. In spite of the limitations, the cooperative action of $^{33}$S and $^{10}$B is an interesting possibility to be studied for accelerator-based neutron sources with non-moderated neutrons. |
id | oai-inspirehep.net-1798180 |
institution | Organización Europea para la Investigación Nuclear |
language | eng |
publishDate | 2020 |
record_format | invenio |
spelling | oai-inspirehep.net-17981802020-08-04T21:50:45Zdoi:10.1016/j.apradiso.2020.109220http://cds.cern.ch/record/2725884engLópez-Casas, IPraena, JArias de Saavedra, FSabaté-Gilarte, MPorras, IExploring neutron capture therapy with $^{33}$S and $^{10}$BThe $^{33}$S(n,α)$^{30}$Si reaction was proposed as cooperative neutron capturer to $^{10}$B(n,α)$^{7}$Li in Neutron Capture Therapy (NCT). At that moment, the available $^{33}$S(n,α)$^{30}$Si cross-section data were scarce and discrepant in key energy ranges for its use in NCT. Since then, three experiments have been carried out at n_TOF facility at CERN and at Institut Laue-Langevin. These new data are used for the calculation of the dose rate on ICRU-4 tissue by using kerma factors, a simplified model of tissue and a 13.45 keV neutron beam, energy of the most important $^{33}$S(n,α)$^{30}$Si resonance. A significant enhancement of the dose rate due to the presence of $^{33}$S is shown. In spite of the limitations, the cooperative action of $^{33}$S and $^{10}$B is an interesting possibility to be studied for accelerator-based neutron sources with non-moderated neutrons.oai:inspirehep.net:17981802020 |
spellingShingle | López-Casas, I Praena, J Arias de Saavedra, F Sabaté-Gilarte, M Porras, I Exploring neutron capture therapy with $^{33}$S and $^{10}$B |
title | Exploring neutron capture therapy with $^{33}$S and $^{10}$B |
title_full | Exploring neutron capture therapy with $^{33}$S and $^{10}$B |
title_fullStr | Exploring neutron capture therapy with $^{33}$S and $^{10}$B |
title_full_unstemmed | Exploring neutron capture therapy with $^{33}$S and $^{10}$B |
title_short | Exploring neutron capture therapy with $^{33}$S and $^{10}$B |
title_sort | exploring neutron capture therapy with $^{33}$s and $^{10}$b |
url | https://dx.doi.org/10.1016/j.apradiso.2020.109220 http://cds.cern.ch/record/2725884 |
work_keys_str_mv | AT lopezcasasi exploringneutroncapturetherapywith33sand10b AT praenaj exploringneutroncapturetherapywith33sand10b AT ariasdesaavedraf exploringneutroncapturetherapywith33sand10b AT sabategilartem exploringneutroncapturetherapywith33sand10b AT porrasi exploringneutroncapturetherapywith33sand10b |