Identifying a nasal gene expression signature associated with hyperinflation and treatment response in severe COPD

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Hyperinflation contributes to dyspnea intensity in COPD. Little is known about the molecular mechanisms underlying hyperinflation and how inhaled corticosteroids (ICS) affect this important aspect of COPD pathophysiology. To investigate the effect of ICS/long-acting β$_{2}$-agonist (LABA) treatment...

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Detalles Bibliográficos
Autores principales: Faiz, Alen, Imkamp, Kai, van der Wiel, Erica, Boudewijn, Ilse M, Koppelman, Gerard H, Brandsma, Corry-Anke, Kerstjens, Huib A M, Timens, Wim, Vroegop, Sebastiaan, Pasma, Henk R, Boersma, Wim G, Wielders, Pascal, van den Elshout, Frank, Mansour, Khaled, Steiling, Katrina, Spira, Avrum, Lenburg, Marc E, Heijink, Irene H, Postma, Dirkje S, van den Berge, Maarten
Lenguaje:eng
Publicado: 2020
Acceso en línea:https://dx.doi.org/10.1038/s41598-020-72551-0
http://cds.cern.ch/record/2744727
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