Downregulation of Dystrophin Expression Occurs across Diverse Tumors, Correlates with the Age of Onset, Staging and Reduced Survival of Patients

SIMPLE SUMMARY: Mutations of the DMD gene, encoding dystrophins, cause Duchenne muscular dystrophy (DMD). We found that while DMD transcription occurs throughout a spectrum of normal tissues, it is frequently downregulated across various malignancies. The molecular signature associated with this dow...

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Detalles Bibliográficos
Autores principales: Alnassar, Nancy, Borczyk, Malgorzata, Tsagkogeorga, Georgia, Korostynski, Michal, Han, Namshik, Górecki, Dariusz C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10000051/
https://www.ncbi.nlm.nih.gov/pubmed/36900171
http://dx.doi.org/10.3390/cancers15051378

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10000051/
https://www.ncbi.nlm.nih.gov/pubmed/36900171
http://dx.doi.org/10.3390/cancers15051378

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