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Downregulation of Dystrophin Expression Occurs across Diverse Tumors, Correlates with the Age of Onset, Staging and Reduced Survival of Patients
SIMPLE SUMMARY: Mutations of the DMD gene, encoding dystrophins, cause Duchenne muscular dystrophy (DMD). We found that while DMD transcription occurs throughout a spectrum of normal tissues, it is frequently downregulated across various malignancies. The molecular signature associated with this dow...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10000051/ https://www.ncbi.nlm.nih.gov/pubmed/36900171 http://dx.doi.org/10.3390/cancers15051378 |