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Somatic, Genetic and Epigenetic Changes in Nephrogenic Rests and Their Role in the Transformation to Wilms Tumors, a Systematic Review

SIMPLE SUMMARY: We reviewed all studies investigating molecular changes in nephrogenic rests (NR), the presumed precursor lesions of Wilms tumors (WT) being the most frequent malignant childhood renal tumors, between 1990 and 2022. Only 23 studies were found, reporting 119 pairs of NR and correspond...

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Detalles Bibliográficos
Autores principales: Bánki, Tessa, Drost, Jarno, van den Heuvel-Eibrink, Marry M., Mavinkurve-Groothuis, Annelies M. C., de Krijger, Ronald R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10000075/
https://www.ncbi.nlm.nih.gov/pubmed/36900155
http://dx.doi.org/10.3390/cancers15051363