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Recurrent syncope in long survivors and its association with geriatric syndromes

OBJECTIVE: Syncope is a common clinical condition in the elderly, associated with significant morbidity and risk of recurrence. Recurrent syncope causing a repeated reduction in the cerebral blood flow can predispose to progressive neurodegeneration, a decline in overall health and functionality. He...

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Autores principales: Bandhu, Kamal, Rao, Akshata, Nehra, Ashima, Dwivedi, Sada Nand, Chakrawarty, Avinash, Dey, Aparajit Ballav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10000258/
https://www.ncbi.nlm.nih.gov/pubmed/36911095
http://dx.doi.org/10.1002/agm2.12240
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author Bandhu, Kamal
Rao, Akshata
Nehra, Ashima
Dwivedi, Sada Nand
Chakrawarty, Avinash
Dey, Aparajit Ballav
author_facet Bandhu, Kamal
Rao, Akshata
Nehra, Ashima
Dwivedi, Sada Nand
Chakrawarty, Avinash
Dey, Aparajit Ballav
author_sort Bandhu, Kamal
collection PubMed
description OBJECTIVE: Syncope is a common clinical condition in the elderly, associated with significant morbidity and risk of recurrence. Recurrent syncope causing a repeated reduction in the cerebral blood flow can predispose to progressive neurodegeneration, a decline in overall health and functionality. Hence, this study was conducted to study the common causes of recurrent syncope and its association with various geriatric syndromes. METHODOLOGY: This case–control study recruited 50 cases of recurrent syncope and 50 controls, aged 75 years and older. A detailed history and sequential evaluation for aetiologies of recurrent syncope were done. Cognition, frailty, activities of daily living, depression, and nutrition were assessed using various scales. RESULTS: Most (80%, 80/100) of the participants were males and the mean age was 80.04 ± 4.3 years. In the syncope group, 42% (21/50) of patients had arrhythmia, and 30% (15/30) had valvular heart disease. Recurrent syncope was significantly associated with lower scores on Montreal cognitive assessment scale (OR: 6.47 P < 0.001), four or more comorbidities (OR: 6.29 P < 0.001), and hearing impairment (OR: 6.21 P < 0.004) on multivariate logistic regression analysis. CONCLUSION: Recurrent syncope is significantly associated with cognitive impairment, the presence of four or more comorbidities, and hearing impairment. Conduction abnormality was the most common etiology of recurrent cardiovascular syncope. Structured evaluation and appropriate management of recurrent syncope might reduce the decline in physical, cognitive, and psychological reserve. A follow‐up longitudinal study is needed to establish this.
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spelling pubmed-100002582023-03-11 Recurrent syncope in long survivors and its association with geriatric syndromes Bandhu, Kamal Rao, Akshata Nehra, Ashima Dwivedi, Sada Nand Chakrawarty, Avinash Dey, Aparajit Ballav Aging Med (Milton) Original Articles OBJECTIVE: Syncope is a common clinical condition in the elderly, associated with significant morbidity and risk of recurrence. Recurrent syncope causing a repeated reduction in the cerebral blood flow can predispose to progressive neurodegeneration, a decline in overall health and functionality. Hence, this study was conducted to study the common causes of recurrent syncope and its association with various geriatric syndromes. METHODOLOGY: This case–control study recruited 50 cases of recurrent syncope and 50 controls, aged 75 years and older. A detailed history and sequential evaluation for aetiologies of recurrent syncope were done. Cognition, frailty, activities of daily living, depression, and nutrition were assessed using various scales. RESULTS: Most (80%, 80/100) of the participants were males and the mean age was 80.04 ± 4.3 years. In the syncope group, 42% (21/50) of patients had arrhythmia, and 30% (15/30) had valvular heart disease. Recurrent syncope was significantly associated with lower scores on Montreal cognitive assessment scale (OR: 6.47 P < 0.001), four or more comorbidities (OR: 6.29 P < 0.001), and hearing impairment (OR: 6.21 P < 0.004) on multivariate logistic regression analysis. CONCLUSION: Recurrent syncope is significantly associated with cognitive impairment, the presence of four or more comorbidities, and hearing impairment. Conduction abnormality was the most common etiology of recurrent cardiovascular syncope. Structured evaluation and appropriate management of recurrent syncope might reduce the decline in physical, cognitive, and psychological reserve. A follow‐up longitudinal study is needed to establish this. John Wiley and Sons Inc. 2023-01-10 /pmc/articles/PMC10000258/ /pubmed/36911095 http://dx.doi.org/10.1002/agm2.12240 Text en © 2023 The Authors. Aging Medicine published by Beijing Hospital and John Wiley & Sons Australia, Ltd. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Articles
Bandhu, Kamal
Rao, Akshata
Nehra, Ashima
Dwivedi, Sada Nand
Chakrawarty, Avinash
Dey, Aparajit Ballav
Recurrent syncope in long survivors and its association with geriatric syndromes
title Recurrent syncope in long survivors and its association with geriatric syndromes
title_full Recurrent syncope in long survivors and its association with geriatric syndromes
title_fullStr Recurrent syncope in long survivors and its association with geriatric syndromes
title_full_unstemmed Recurrent syncope in long survivors and its association with geriatric syndromes
title_short Recurrent syncope in long survivors and its association with geriatric syndromes
title_sort recurrent syncope in long survivors and its association with geriatric syndromes
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10000258/
https://www.ncbi.nlm.nih.gov/pubmed/36911095
http://dx.doi.org/10.1002/agm2.12240
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