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Evaluation of risk scores as predictors of mortality and hospital length of stay for older COVID‐19 patients
OBJECTIVE: This study was intended to research the sensitivity of the Charlson Comorbidity Index (CCI), COVID‐GRAM, and MuLBSTA risk scores for hospital length of stay (LOS) and mortality in older patients hospitalized with coronavirus disease 2019 (COVID‐19). METHODS: A total of 217 patients (119 w...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10000259/ https://www.ncbi.nlm.nih.gov/pubmed/36911090 http://dx.doi.org/10.1002/agm2.12238 |
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author | Buyukaydin, Banu Karaaslan, Tahsin Uysal, Omer |
author_facet | Buyukaydin, Banu Karaaslan, Tahsin Uysal, Omer |
author_sort | Buyukaydin, Banu |
collection | PubMed |
description | OBJECTIVE: This study was intended to research the sensitivity of the Charlson Comorbidity Index (CCI), COVID‐GRAM, and MuLBSTA risk scores for hospital length of stay (LOS) and mortality in older patients hospitalized with coronavirus disease 2019 (COVID‐19). METHODS: A total of 217 patients (119 women) were included in the study. The first clinical signs, comorbidities, laboratory and radiology findings, and hospital LOS were recorded for each patient. The CCI, COVID‐GRAM, and MuLBSTA risk scores were calculated, and their sensitivities for hospital LOS and mortality were evaluated using receiver operating characteristic (ROC) curve analysis. RESULTS: Of the hospitalized patients, 59 (27.2%) were followed in the intensive care unit, and mortality developed in 44 (20.3%). The CCI positively correlated with COVID‐GRAM and MuLBSTA scores (P < 0.001). COVID‐GRAM and MuLBSTA results correlated with LOS and mortality (P < 0.001). According to the ROC curve analysis, the cutoff points for mortality were 5 for CCI, 169 for COVID‐GRAM, and 9 for MuLBSTA. CONCLUSION: Older patients with comorbidities are the major risk group for severe COVID‐19. COVID‐GRAM and MuLBSTA scores appear to be sensitive and reliable mortality indicators for these patients. |
format | Online Article Text |
id | pubmed-10000259 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-100002592023-03-11 Evaluation of risk scores as predictors of mortality and hospital length of stay for older COVID‐19 patients Buyukaydin, Banu Karaaslan, Tahsin Uysal, Omer Aging Med (Milton) Original Articles OBJECTIVE: This study was intended to research the sensitivity of the Charlson Comorbidity Index (CCI), COVID‐GRAM, and MuLBSTA risk scores for hospital length of stay (LOS) and mortality in older patients hospitalized with coronavirus disease 2019 (COVID‐19). METHODS: A total of 217 patients (119 women) were included in the study. The first clinical signs, comorbidities, laboratory and radiology findings, and hospital LOS were recorded for each patient. The CCI, COVID‐GRAM, and MuLBSTA risk scores were calculated, and their sensitivities for hospital LOS and mortality were evaluated using receiver operating characteristic (ROC) curve analysis. RESULTS: Of the hospitalized patients, 59 (27.2%) were followed in the intensive care unit, and mortality developed in 44 (20.3%). The CCI positively correlated with COVID‐GRAM and MuLBSTA scores (P < 0.001). COVID‐GRAM and MuLBSTA results correlated with LOS and mortality (P < 0.001). According to the ROC curve analysis, the cutoff points for mortality were 5 for CCI, 169 for COVID‐GRAM, and 9 for MuLBSTA. CONCLUSION: Older patients with comorbidities are the major risk group for severe COVID‐19. COVID‐GRAM and MuLBSTA scores appear to be sensitive and reliable mortality indicators for these patients. John Wiley and Sons Inc. 2023-01-10 /pmc/articles/PMC10000259/ /pubmed/36911090 http://dx.doi.org/10.1002/agm2.12238 Text en © 2023 The Authors. Aging Medicine published by Beijing Hospital and John Wiley & Sons Australia, Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made. |
spellingShingle | Original Articles Buyukaydin, Banu Karaaslan, Tahsin Uysal, Omer Evaluation of risk scores as predictors of mortality and hospital length of stay for older COVID‐19 patients |
title | Evaluation of risk scores as predictors of mortality and hospital length of stay for older COVID‐19 patients |
title_full | Evaluation of risk scores as predictors of mortality and hospital length of stay for older COVID‐19 patients |
title_fullStr | Evaluation of risk scores as predictors of mortality and hospital length of stay for older COVID‐19 patients |
title_full_unstemmed | Evaluation of risk scores as predictors of mortality and hospital length of stay for older COVID‐19 patients |
title_short | Evaluation of risk scores as predictors of mortality and hospital length of stay for older COVID‐19 patients |
title_sort | evaluation of risk scores as predictors of mortality and hospital length of stay for older covid‐19 patients |
topic | Original Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10000259/ https://www.ncbi.nlm.nih.gov/pubmed/36911090 http://dx.doi.org/10.1002/agm2.12238 |
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