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EF-24, a Curcumin Analog, Inhibits Cancer Cell Invasion in Human Nasopharyngeal Carcinoma through Transcriptional Suppression of Matrix Metalloproteinase-9 Gene Expression
SIMPLE SUMMARY: EF-24 has exhibited many anti-cancer properties and enhanced bioavailability over curcumin. We demonstrated that through interfering with the nuclear translocation of NF-κB and the activation of JNK, EF-24 inhibited MMP-9 gene transcription, repressing NPC invasion. These findings pr...
Autores principales: | Su, Shih-Chi, Hsin, Chung-Han, Lu, Yen-Ting, Chuang, Chun-Yi, Ho, Yu-Ting, Yeh, Fang-Ling, Yang, Shun-Fa, Lin, Chiao-Wen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10000445/ https://www.ncbi.nlm.nih.gov/pubmed/36900342 http://dx.doi.org/10.3390/cancers15051552 |
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