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Sulforaphane Potentiates Gemcitabine-Mediated Anti-Cancer Effects against Intrahepatic Cholangiocarcinoma by Inhibiting HDAC Activity

Intrahepatic cholangiocarcinoma (iCCA), the second most common primary liver cancer, has high mortality rates because of its limited treatment options and acquired resistance to chemotherapy. Sulforaphane (SFN), a naturally occurring organosulfur compound found in cruciferous vegetables, exhibits mu...

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Detalles Bibliográficos
Autores principales: Tomooka, Fumimasa, Kaji, Kosuke, Nishimura, Norihisa, Kubo, Takahiro, Iwai, Satoshi, Shibamoto, Akihiko, Suzuki, Junya, Kitagawa, Koh, Namisaki, Tadashi, Akahane, Takemi, Mitoro, Akira, Yoshiji, Hitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10000472/
https://www.ncbi.nlm.nih.gov/pubmed/36899823
http://dx.doi.org/10.3390/cells12050687

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