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Sulforaphane Potentiates Gemcitabine-Mediated Anti-Cancer Effects against Intrahepatic Cholangiocarcinoma by Inhibiting HDAC Activity
Intrahepatic cholangiocarcinoma (iCCA), the second most common primary liver cancer, has high mortality rates because of its limited treatment options and acquired resistance to chemotherapy. Sulforaphane (SFN), a naturally occurring organosulfur compound found in cruciferous vegetables, exhibits mu...
Autores principales: | Tomooka, Fumimasa, Kaji, Kosuke, Nishimura, Norihisa, Kubo, Takahiro, Iwai, Satoshi, Shibamoto, Akihiko, Suzuki, Junya, Kitagawa, Koh, Namisaki, Tadashi, Akahane, Takemi, Mitoro, Akira, Yoshiji, Hitoshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10000472/ https://www.ncbi.nlm.nih.gov/pubmed/36899823 http://dx.doi.org/10.3390/cells12050687 |
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