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Syndrome Pattern Recognition Method Using Sensed Patient Data for Neurodegenerative Disease Progression Identification

Neurodegenerative diseases are a group of conditions that involve the progressive loss of function of neurons in the brain and spinal cord. These conditions can result in a wide range of symptoms, such as difficulty with movement, speech, and cognition. The causes of neurodegenerative diseases are p...

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Autores principales: Anjum, Mohd, Shahab, Sana, Yu, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10000542/
https://www.ncbi.nlm.nih.gov/pubmed/36900031
http://dx.doi.org/10.3390/diagnostics13050887
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author Anjum, Mohd
Shahab, Sana
Yu, Yang
author_facet Anjum, Mohd
Shahab, Sana
Yu, Yang
author_sort Anjum, Mohd
collection PubMed
description Neurodegenerative diseases are a group of conditions that involve the progressive loss of function of neurons in the brain and spinal cord. These conditions can result in a wide range of symptoms, such as difficulty with movement, speech, and cognition. The causes of neurodegenerative diseases are poorly understood, but many factors are believed to contribute to the development of these conditions. The most important risk factors include ageing, genetics, abnormal medical conditions, toxins, and environmental exposures. A slow decline in visible cognitive functions characterises the progression of these diseases. If left unattended or unnoticed, disease progression can result in serious issues such as the cessation of motor function or even paralysis. Therefore, early recognition of neurodegenerative diseases is becoming increasingly important in modern healthcare. Many sophisticated artificial intelligence technologies are incorporated into modern healthcare systems for the early recognition of these diseases. This research article introduces a Syndrome-dependent Pattern Recognition Method for the early detection and progression monitoring of neurodegenerative diseases. The proposed method determines the variance between normal and abnormal intrinsic neural connectivity data. The observed data is combined with previous and healthy function examination data to identify the variance. In this combined analysis, deep recurrent learning is exploited by tuning the analysis layer based on variance suppressed by identifying normal and abnormal patterns in the combined analysis. This variance from different patterns is recurrently used to train the learning model for maximising of recognition accuracy. The proposed method achieves 16.77% high accuracy, 10.55% high precision, and 7.69% high pattern verification. It reduces the variance and verification time by 12.08% and 12.02%, respectively.
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spelling pubmed-100005422023-03-11 Syndrome Pattern Recognition Method Using Sensed Patient Data for Neurodegenerative Disease Progression Identification Anjum, Mohd Shahab, Sana Yu, Yang Diagnostics (Basel) Article Neurodegenerative diseases are a group of conditions that involve the progressive loss of function of neurons in the brain and spinal cord. These conditions can result in a wide range of symptoms, such as difficulty with movement, speech, and cognition. The causes of neurodegenerative diseases are poorly understood, but many factors are believed to contribute to the development of these conditions. The most important risk factors include ageing, genetics, abnormal medical conditions, toxins, and environmental exposures. A slow decline in visible cognitive functions characterises the progression of these diseases. If left unattended or unnoticed, disease progression can result in serious issues such as the cessation of motor function or even paralysis. Therefore, early recognition of neurodegenerative diseases is becoming increasingly important in modern healthcare. Many sophisticated artificial intelligence technologies are incorporated into modern healthcare systems for the early recognition of these diseases. This research article introduces a Syndrome-dependent Pattern Recognition Method for the early detection and progression monitoring of neurodegenerative diseases. The proposed method determines the variance between normal and abnormal intrinsic neural connectivity data. The observed data is combined with previous and healthy function examination data to identify the variance. In this combined analysis, deep recurrent learning is exploited by tuning the analysis layer based on variance suppressed by identifying normal and abnormal patterns in the combined analysis. This variance from different patterns is recurrently used to train the learning model for maximising of recognition accuracy. The proposed method achieves 16.77% high accuracy, 10.55% high precision, and 7.69% high pattern verification. It reduces the variance and verification time by 12.08% and 12.02%, respectively. MDPI 2023-02-26 /pmc/articles/PMC10000542/ /pubmed/36900031 http://dx.doi.org/10.3390/diagnostics13050887 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Anjum, Mohd
Shahab, Sana
Yu, Yang
Syndrome Pattern Recognition Method Using Sensed Patient Data for Neurodegenerative Disease Progression Identification
title Syndrome Pattern Recognition Method Using Sensed Patient Data for Neurodegenerative Disease Progression Identification
title_full Syndrome Pattern Recognition Method Using Sensed Patient Data for Neurodegenerative Disease Progression Identification
title_fullStr Syndrome Pattern Recognition Method Using Sensed Patient Data for Neurodegenerative Disease Progression Identification
title_full_unstemmed Syndrome Pattern Recognition Method Using Sensed Patient Data for Neurodegenerative Disease Progression Identification
title_short Syndrome Pattern Recognition Method Using Sensed Patient Data for Neurodegenerative Disease Progression Identification
title_sort syndrome pattern recognition method using sensed patient data for neurodegenerative disease progression identification
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10000542/
https://www.ncbi.nlm.nih.gov/pubmed/36900031
http://dx.doi.org/10.3390/diagnostics13050887
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