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A Web-Based Platform for the Automatic Stratification of ARDS Severity

Acute respiratory distress syndrome (ARDS), including severe pulmonary COVID infection, is associated with a high mortality rate. It is crucial to detect ARDS early, as a late diagnosis may lead to serious complications in treatment. One of the challenges in ARDS diagnosis is chest X-ray (CXR) inter...

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Autores principales: Yahyatabar, Mohammad, Jouvet, Philippe, Fily, Donatien, Rambaud, Jérome, Levy, Michaël, Khemani, Robinder G., Cheriet, Farida
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10000955/
https://www.ncbi.nlm.nih.gov/pubmed/36900077
http://dx.doi.org/10.3390/diagnostics13050933
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author Yahyatabar, Mohammad
Jouvet, Philippe
Fily, Donatien
Rambaud, Jérome
Levy, Michaël
Khemani, Robinder G.
Cheriet, Farida
author_facet Yahyatabar, Mohammad
Jouvet, Philippe
Fily, Donatien
Rambaud, Jérome
Levy, Michaël
Khemani, Robinder G.
Cheriet, Farida
author_sort Yahyatabar, Mohammad
collection PubMed
description Acute respiratory distress syndrome (ARDS), including severe pulmonary COVID infection, is associated with a high mortality rate. It is crucial to detect ARDS early, as a late diagnosis may lead to serious complications in treatment. One of the challenges in ARDS diagnosis is chest X-ray (CXR) interpretation. ARDS causes diffuse infiltrates through the lungs that must be identified using chest radiography. In this paper, we present a web-based platform leveraging artificial intelligence (AI) to automatically assess pediatric ARDS (PARDS) using CXR images. Our system computes a severity score to identify and grade ARDS in CXR images. Moreover, the platform provides an image highlighting the lung fields, which can be utilized for prospective AI-based systems. A deep learning (DL) approach is employed to analyze the input data. A novel DL model, named Dense-Ynet, is trained using a CXR dataset in which clinical specialists previously labelled the two halves (upper and lower) of each lung. The assessment results show that our platform achieves a recall rate of  [Formula: see text]  and a precision of  [Formula: see text]. The web platform, named PARDS-CxR, assigns severity scores to input CXR images that are compatible with current definitions of ARDS and PARDS. Once it has undergone external validation, PARDS-CxR will serve as an essential component in a clinical AI framework for diagnosing ARDS.
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spelling pubmed-100009552023-03-11 A Web-Based Platform for the Automatic Stratification of ARDS Severity Yahyatabar, Mohammad Jouvet, Philippe Fily, Donatien Rambaud, Jérome Levy, Michaël Khemani, Robinder G. Cheriet, Farida Diagnostics (Basel) Article Acute respiratory distress syndrome (ARDS), including severe pulmonary COVID infection, is associated with a high mortality rate. It is crucial to detect ARDS early, as a late diagnosis may lead to serious complications in treatment. One of the challenges in ARDS diagnosis is chest X-ray (CXR) interpretation. ARDS causes diffuse infiltrates through the lungs that must be identified using chest radiography. In this paper, we present a web-based platform leveraging artificial intelligence (AI) to automatically assess pediatric ARDS (PARDS) using CXR images. Our system computes a severity score to identify and grade ARDS in CXR images. Moreover, the platform provides an image highlighting the lung fields, which can be utilized for prospective AI-based systems. A deep learning (DL) approach is employed to analyze the input data. A novel DL model, named Dense-Ynet, is trained using a CXR dataset in which clinical specialists previously labelled the two halves (upper and lower) of each lung. The assessment results show that our platform achieves a recall rate of  [Formula: see text]  and a precision of  [Formula: see text]. The web platform, named PARDS-CxR, assigns severity scores to input CXR images that are compatible with current definitions of ARDS and PARDS. Once it has undergone external validation, PARDS-CxR will serve as an essential component in a clinical AI framework for diagnosing ARDS. MDPI 2023-03-01 /pmc/articles/PMC10000955/ /pubmed/36900077 http://dx.doi.org/10.3390/diagnostics13050933 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Yahyatabar, Mohammad
Jouvet, Philippe
Fily, Donatien
Rambaud, Jérome
Levy, Michaël
Khemani, Robinder G.
Cheriet, Farida
A Web-Based Platform for the Automatic Stratification of ARDS Severity
title A Web-Based Platform for the Automatic Stratification of ARDS Severity
title_full A Web-Based Platform for the Automatic Stratification of ARDS Severity
title_fullStr A Web-Based Platform for the Automatic Stratification of ARDS Severity
title_full_unstemmed A Web-Based Platform for the Automatic Stratification of ARDS Severity
title_short A Web-Based Platform for the Automatic Stratification of ARDS Severity
title_sort web-based platform for the automatic stratification of ards severity
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10000955/
https://www.ncbi.nlm.nih.gov/pubmed/36900077
http://dx.doi.org/10.3390/diagnostics13050933
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