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A Novel Phenazine Analog, CPUL1, Suppresses Autophagic Flux and Proliferation in Hepatocellular Carcinoma: Insight from Integrated Transcriptomic and Metabolomic Analysis

SIMPLE SUMMARY: CPUL1 exhibits antitumor properties against hepatocellular carcinoma (HCC), although the underlying mechanisms remain unclear. Our study provides a comprehensive overview of the properties and molecular mechanisms of CPUL1 anti-HCC using transcriptomics and metabolomics and highlight...

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Những tác giả chính: Chen, Jiaqin, Feng, Dong, Lu, Yuanyuan, Zhang, Yanjun, Jiang, Hanxiang, Yuan, Man, Xu, Yifan, Zou, Jianjun, Zhu, Yubing, Zhang, Jingjing, Ge, Chun, Wang, Ying
Định dạng: Online Bài viết Texto
Ngôn ngữ:English
Được phát hành: MDPI 2023
Những chủ đề:
Truy cập trực tuyến:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10001020/
https://www.ncbi.nlm.nih.gov/pubmed/36900398
http://dx.doi.org/10.3390/cancers15051607