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Impact of Breathing Phase, Liver Segment, and Prandial State on Ultrasound Shear Wave Speed, Shear Wave Dispersion, and Attenuation Imaging of the Liver in Healthy Volunteers

Objectives: Measurement location and patient state can impact noninvasive liver assessment and change clinical staging in ultrasound examinations. Research into differences exists for Shear Wave Speed (SWS) and Attenuation Imaging (ATI), but not for Shear Wave Dispersion (SWD). The aim of this study...

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Autores principales: Paverd, Catherine, Kupfer, Sivert, Kirchner, Iara Nascimento, Nambiar, Sherin, Martin, Alexander, Korta Martiartu, Naiara, Frauenfelder, Thomas, Rominger, Marga B., Ruby, Lisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10001107/
https://www.ncbi.nlm.nih.gov/pubmed/36900133
http://dx.doi.org/10.3390/diagnostics13050989
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author Paverd, Catherine
Kupfer, Sivert
Kirchner, Iara Nascimento
Nambiar, Sherin
Martin, Alexander
Korta Martiartu, Naiara
Frauenfelder, Thomas
Rominger, Marga B.
Ruby, Lisa
author_facet Paverd, Catherine
Kupfer, Sivert
Kirchner, Iara Nascimento
Nambiar, Sherin
Martin, Alexander
Korta Martiartu, Naiara
Frauenfelder, Thomas
Rominger, Marga B.
Ruby, Lisa
author_sort Paverd, Catherine
collection PubMed
description Objectives: Measurement location and patient state can impact noninvasive liver assessment and change clinical staging in ultrasound examinations. Research into differences exists for Shear Wave Speed (SWS) and Attenuation Imaging (ATI), but not for Shear Wave Dispersion (SWD). The aim of this study is to assess the effect of breathing phase, liver lobe, and prandial state on SWS, SWD, and ATI ultrasound measurements. Methods: Two experienced examiners performed SWS, SWD, and ATI measurements in 20 healthy volunteers using a Canon Aplio i800 system. Measurements were taken in the recommended condition (right lobe, following expiration, fasting state), as well as (a) following inspiration, (b) in the left lobe, and (c) in a nonfasting state. Results: SWS and SWD measurements were strongly correlated (r = 0.805, p < 0.001). Mean SWS was 1.34 ± 0.13 m/s in the recommended measurement position and did not change significantly under any condition. Mean SWD was 10.81 ± 2.05 m/s/kHz in the standard condition and significantly increased to 12.18 ± 1.41 m/s/kHz in the left lobe. Individual SWD measurements in the left lobe also had the highest average coefficient of variation (19.68%). No significant differences were found for ATI. Conclusion: Breathing and prandial state did not significantly affect SWS, SWD, and ATI values. SWS and SWD measurements were strongly correlated. SWD measurements in the left lobe showed a higher individual measurement variability. Interobserver agreement was moderate to good.
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spelling pubmed-100011072023-03-11 Impact of Breathing Phase, Liver Segment, and Prandial State on Ultrasound Shear Wave Speed, Shear Wave Dispersion, and Attenuation Imaging of the Liver in Healthy Volunteers Paverd, Catherine Kupfer, Sivert Kirchner, Iara Nascimento Nambiar, Sherin Martin, Alexander Korta Martiartu, Naiara Frauenfelder, Thomas Rominger, Marga B. Ruby, Lisa Diagnostics (Basel) Article Objectives: Measurement location and patient state can impact noninvasive liver assessment and change clinical staging in ultrasound examinations. Research into differences exists for Shear Wave Speed (SWS) and Attenuation Imaging (ATI), but not for Shear Wave Dispersion (SWD). The aim of this study is to assess the effect of breathing phase, liver lobe, and prandial state on SWS, SWD, and ATI ultrasound measurements. Methods: Two experienced examiners performed SWS, SWD, and ATI measurements in 20 healthy volunteers using a Canon Aplio i800 system. Measurements were taken in the recommended condition (right lobe, following expiration, fasting state), as well as (a) following inspiration, (b) in the left lobe, and (c) in a nonfasting state. Results: SWS and SWD measurements were strongly correlated (r = 0.805, p < 0.001). Mean SWS was 1.34 ± 0.13 m/s in the recommended measurement position and did not change significantly under any condition. Mean SWD was 10.81 ± 2.05 m/s/kHz in the standard condition and significantly increased to 12.18 ± 1.41 m/s/kHz in the left lobe. Individual SWD measurements in the left lobe also had the highest average coefficient of variation (19.68%). No significant differences were found for ATI. Conclusion: Breathing and prandial state did not significantly affect SWS, SWD, and ATI values. SWS and SWD measurements were strongly correlated. SWD measurements in the left lobe showed a higher individual measurement variability. Interobserver agreement was moderate to good. MDPI 2023-03-05 /pmc/articles/PMC10001107/ /pubmed/36900133 http://dx.doi.org/10.3390/diagnostics13050989 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Paverd, Catherine
Kupfer, Sivert
Kirchner, Iara Nascimento
Nambiar, Sherin
Martin, Alexander
Korta Martiartu, Naiara
Frauenfelder, Thomas
Rominger, Marga B.
Ruby, Lisa
Impact of Breathing Phase, Liver Segment, and Prandial State on Ultrasound Shear Wave Speed, Shear Wave Dispersion, and Attenuation Imaging of the Liver in Healthy Volunteers
title Impact of Breathing Phase, Liver Segment, and Prandial State on Ultrasound Shear Wave Speed, Shear Wave Dispersion, and Attenuation Imaging of the Liver in Healthy Volunteers
title_full Impact of Breathing Phase, Liver Segment, and Prandial State on Ultrasound Shear Wave Speed, Shear Wave Dispersion, and Attenuation Imaging of the Liver in Healthy Volunteers
title_fullStr Impact of Breathing Phase, Liver Segment, and Prandial State on Ultrasound Shear Wave Speed, Shear Wave Dispersion, and Attenuation Imaging of the Liver in Healthy Volunteers
title_full_unstemmed Impact of Breathing Phase, Liver Segment, and Prandial State on Ultrasound Shear Wave Speed, Shear Wave Dispersion, and Attenuation Imaging of the Liver in Healthy Volunteers
title_short Impact of Breathing Phase, Liver Segment, and Prandial State on Ultrasound Shear Wave Speed, Shear Wave Dispersion, and Attenuation Imaging of the Liver in Healthy Volunteers
title_sort impact of breathing phase, liver segment, and prandial state on ultrasound shear wave speed, shear wave dispersion, and attenuation imaging of the liver in healthy volunteers
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10001107/
https://www.ncbi.nlm.nih.gov/pubmed/36900133
http://dx.doi.org/10.3390/diagnostics13050989
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