Discovering Synergistic Compounds with BYL-719 in PI3K Overactivated Basal-like PDXs

SIMPLE SUMMARY: Basal-like breast cancers comprise the majority of triple-negative breast cancers (TNBC) and lack effective treatment options that have a sustained response. Part of the reason that they are hard to eliminate is that they exhibit high levels of genomic instability and cellular divers...

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Detalles Bibliográficos
Autores principales: Boyd, David C., Zboril, Emily K., Olex, Amy L., Leftwich, Tess J., Hairr, Nicole S., Byers, Holly A., Valentine, Aaron D., Altman, Julia E., Alzubi, Mohammad A., Grible, Jacqueline M., Turner, Scott A., Ferreira-Gonzalez, Andrea, Dozmorov, Mikhail G., Harrell, J. Chuck
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10001201/
https://www.ncbi.nlm.nih.gov/pubmed/36900375
http://dx.doi.org/10.3390/cancers15051582

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