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Information–Thermodynamic Method for the Study of Proliferation of Organized Cellular Structure
The aim of the article was to develop an innovative method for the study of cell proliferation based on the information–thermodynamic approach, including the mathematical ratio—the entropy of cell proliferation and an algorithm for the calculation of fractal dimension of the cellular structure. Appr...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10001364/ https://www.ncbi.nlm.nih.gov/pubmed/36899867 http://dx.doi.org/10.3390/cells12050731 |
| Sumario: | The aim of the article was to develop an innovative method for the study of cell proliferation based on the information–thermodynamic approach, including the mathematical ratio—the entropy of cell proliferation and an algorithm for the calculation of fractal dimension of the cellular structure. Approbation of this method with pulsed electromagnetic impact on culture in vitro was implemented. It is shown on the basis of experimental data that the organized cellular structure of juvenile human fibroblasts is a fractal. The method makes it possible to determine the stability of the effect on cell proliferation. The prospects for the application of the developed method are discussed. |
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