Information–Thermodynamic Method for the Study of Proliferation of Organized Cellular Structure

The aim of the article was to develop an innovative method for the study of cell proliferation based on the information–thermodynamic approach, including the mathematical ratio—the entropy of cell proliferation and an algorithm for the calculation of fractal dimension of the cellular structure. Appr...

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Detalles Bibliográficos
Autores principales: Volov, Vyacheslav T., Volova, Larisa T., Kolsanov, Alexander V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10001364/
https://www.ncbi.nlm.nih.gov/pubmed/36899867
http://dx.doi.org/10.3390/cells12050731
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author Volov, Vyacheslav T.
Volova, Larisa T.
Kolsanov, Alexander V.
author_facet Volov, Vyacheslav T.
Volova, Larisa T.
Kolsanov, Alexander V.
author_sort Volov, Vyacheslav T.
collection PubMed
description The aim of the article was to develop an innovative method for the study of cell proliferation based on the information–thermodynamic approach, including the mathematical ratio—the entropy of cell proliferation and an algorithm for the calculation of fractal dimension of the cellular structure. Approbation of this method with pulsed electromagnetic impact on culture in vitro was implemented. It is shown on the basis of experimental data that the organized cellular structure of juvenile human fibroblasts is a fractal. The method makes it possible to determine the stability of the effect on cell proliferation. The prospects for the application of the developed method are discussed.
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spelling pubmed-100013642023-03-11 Information–Thermodynamic Method for the Study of Proliferation of Organized Cellular Structure Volov, Vyacheslav T. Volova, Larisa T. Kolsanov, Alexander V. Cells Communication The aim of the article was to develop an innovative method for the study of cell proliferation based on the information–thermodynamic approach, including the mathematical ratio—the entropy of cell proliferation and an algorithm for the calculation of fractal dimension of the cellular structure. Approbation of this method with pulsed electromagnetic impact on culture in vitro was implemented. It is shown on the basis of experimental data that the organized cellular structure of juvenile human fibroblasts is a fractal. The method makes it possible to determine the stability of the effect on cell proliferation. The prospects for the application of the developed method are discussed. MDPI 2023-02-24 /pmc/articles/PMC10001364/ /pubmed/36899867 http://dx.doi.org/10.3390/cells12050731 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Communication
Volov, Vyacheslav T.
Volova, Larisa T.
Kolsanov, Alexander V.
Information–Thermodynamic Method for the Study of Proliferation of Organized Cellular Structure
title Information–Thermodynamic Method for the Study of Proliferation of Organized Cellular Structure
title_full Information–Thermodynamic Method for the Study of Proliferation of Organized Cellular Structure
title_fullStr Information–Thermodynamic Method for the Study of Proliferation of Organized Cellular Structure
title_full_unstemmed Information–Thermodynamic Method for the Study of Proliferation of Organized Cellular Structure
title_short Information–Thermodynamic Method for the Study of Proliferation of Organized Cellular Structure
title_sort information–thermodynamic method for the study of proliferation of organized cellular structure
topic Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10001364/
https://www.ncbi.nlm.nih.gov/pubmed/36899867
http://dx.doi.org/10.3390/cells12050731
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