Cargando…

Lacrimal Gland Epithelial Cells Shape Immune Responses through the Modulation of Inflammasomes and Lipid Metabolism

Lacrimal gland inflammation triggers dry eye disease through impaired tear secretion by the epithelium. As aberrant inflammasome activation occurs in autoimmune disorders including Sjögren’s syndrome, we analyzed the inflammasome pathway during acute and chronic inflammation and investigated its pot...

Descripción completa

Detalles Bibliográficos
Autores principales:	Delcroix, Vanessa, Mauduit, Olivier, Yang, Menglu, Srivastava, Amrita, Umazume, Takeshi, de Paiva, Cintia S., Shestopalov, Valery I., Dartt, Darlene A., Makarenkova, Helen P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10001612/ https://www.ncbi.nlm.nih.gov/pubmed/36901740 http://dx.doi.org/10.3390/ijms24054309

Ejemplares similares

Spatial transcriptomics of the lacrimal gland features macrophage activity and epithelium metabolism as key alterations during chronic inflammation
por: Mauduit, Olivier, et al.
Publicado: (2022)

The First Transcriptomic Atlas of the Adult Lacrimal Gland Reveals Epithelial Complexity and Identifies Novel Progenitor Cells in Mice
por: Delcroix, Vanessa, et al.
Publicado: (2023)

Origin and Lineage Plasticity of Endogenous Lacrimal Gland Epithelial Stem/Progenitor Cells
por: Basova, Liana, et al.
Publicado: (2020)

Manipulation of Panx1 Activity Increases the Engraftment of Transplanted Lacrimal Gland Epithelial Progenitor Cells
por: Basova, Liana V., et al.
Publicado: (2017)

Lacrimal Gland Repair Using Progenitor Cells
por: Gromova, Anastasia, et al.
Publicado: (2016)

A mesenchymal to epithelial switch in Fgf10 expression specifies an evolutionary-conserved population of ionocytes in salivary glands
por: Mauduit, Olivier, et al.
Publicado: (2022)

Alteration in Nerves and Neurotransmitter Stimulation of Lacrimal Gland Secretion in the TSP-1(−/−) Mouse Model of Aqueous Deficiency Dry Eye
por: Bhattacharya, Sumit, et al.
Publicado: (2018)

Age-related Autoimmune Changes in Lacrimal Glands
por: de Souza, Rodrigo G., et al.
Publicado: (2019)

Our search of immune invaders in the aged lacrimal gland
por: Trujillo-Vargas, Claudia M., et al.
Publicado: (2023)

Role of FGF10/FGFR2b Signaling in Homeostasis and Regeneration of Adult Lacrimal Gland and Corneal Epithelium Proliferation
por: Finburgh, Emma N., et al.
Publicado: (2023)

Heterochronic Parabiosis Causes Dacryoadenitis in Young Lacrimal Glands
por: Scholand, Kaitlin K., et al.
Publicado: (2023)

Role of the Phospholipase C Pathway and Calcium Mobilization in Oxytocin-Induced Contraction of Lacrimal Gland Myoepithelial Cells
por: Gárriz, Angela, et al.
Publicado: (2021)

FGF Gradient Controls Boundary Position Between Proliferating and Differentiating Cells and Regulates Lacrimal Gland Growth Dynamics
por: Thotakura, Suharika, et al.
Publicado: (2019)

Lacrimal Gland Microenvironment Changes After Obstruction of Lacrimal Gland Ducts
por: He, Xin, et al.
Publicado: (2022)

Amyloidosis of lacrimal gland
por: Kumar, Vinod, et al.
Publicado: (2010)

Amyloidosis of lacrimal gland
por: Prabhakaran, Venkatesh C, et al.
Publicado: (2009)

Lacrimal gland myxoma
por: Parikh, Drushti, et al.
Publicado: (2017)

The role of pannexin hemichannels in inflammation and regeneration
por: Makarenkova, Helen P., et al.
Publicado: (2014)

Aquaporin5 Deficiency Aggravates ROS/NLRP3 Inflammasome-Mediated Pyroptosis in the Lacrimal Glands
por: Cao, Xin, et al.
Publicado: (2023)

Morphological Features of the Porcine Lacrimal Gland and Its Compatibility for Human Lacrimal Gland Xenografting
por: Henker, Robert, et al.
Publicado: (2013)

Pleomorphic adenoma of lacrimal gland
por: Binatli, Özcan, et al.
Publicado: (2013)

Primary Adenocarcinoma of the Lacrimal Gland
por: Baek, Sang-Oon, et al.
Publicado: (2012)

Unusual lymphoma of lacrimal gland
por: Gupta, Pankaj, et al.
Publicado: (2014)

Isolated lacrimal gland involvement in Rosai-Dorfman-Destombes disease
por: Gulwani, Hanni, et al.
Publicado: (2008)

The Radiological Spectrum of Orbital Pathologies that Involve the Lacrimal Gland and the Lacrimal Fossa
por: Jung, Won Sang, et al.
Publicado: (2007)

Microvascular anastomosis of the human lacrimal gland: a concept study towards transplantation of the human lacrimal gland
por: Holtmann, Christoph, et al.
Publicado: (2022)

Characterization of cultivated murine lacrimal gland epithelial cells
por: Kobayashi, Shinya, et al.
Publicado: (2012)

Lacrimal Glands: Size Does Matter!
por: Mohan, Suyash, et al.
Publicado: (2011)

Amyloidosis of lacrimal gland: Authors’ reply
por: Murthy, Sowmya Raveendra, et al.
Publicado: (2010)

Human Lacrimal Gland Gene Expression
por: Aakalu, Vinay Kumar, et al.
Publicado: (2017)

Plexiform Neurofibroma Involving the Lacrimal Gland
por: Hofsli, Mikael, et al.
Publicado: (2017)

An unusual presentation of lacrimal gland dirofilariasis
por: Sethi, Amit, et al.
Publicado: (2017)

Lacrimal Gland Amyloidosis in an Elderly Patient
por: Nagai, Toshiya, et al.
Publicado: (2020)

Advances in clinical examination of lacrimal gland
por: Lin, Yuan, et al.
Publicado: (2023)

Ectopic lacrimal gland in a complex choristoma involving the lacrimal sac fossa
por: Ali, Mohammad Javed, et al.
Publicado: (2017)

Establishment of long-term serum-free culture for lacrimal gland stem cells aiming at lacrimal gland repair
por: Xiao, Sa, et al.
Publicado: (2020)

The two faces of pannexins: new roles in inflammation and repair
por: Makarenkova, Helen P, et al.
Publicado: (2018)

Establishment of functional epithelial organoids from human lacrimal glands
por: Jeong, Sang Yun, et al.
Publicado: (2021)

Epithelial Lacrimal Gland Tumours in Nigeria: Clinicopathological Features and Treatment
por: Fasina, Oluyemi, et al.
Publicado: (2020)

Myoepithelial cell-driven acini contraction in response to oxytocin receptor stimulation is impaired in lacrimal glands of Sjögren’s syndrome animal models
por: Hawley, Dillon, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_snjul7s5auoed10uvnebat05di