Cargando…

Glycyl-tRNA Synthetase (GARS) Expression Is Associated with Prostate Cancer Progression and Its Inhibition Decreases Migration, and Invasion In Vitro

Glycyl-tRNA synthetase (GARS) is a potential oncogene associated with poor overall survival in various cancers. However, its role in prostate cancer (PCa) has not been investigated. Protein expression of GARS was investigated in benign, incidental, advanced, and castrate-resistant PCa (CRPC) patient...

Descripción completa

Detalles Bibliográficos
Autores principales:	Khosh Kish, Ealia, Gamallat, Yaser, Choudhry, Muhammad, Ghosh, Sunita, Seyedi, Sima, Bismar, Tarek A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10001614/ https://www.ncbi.nlm.nih.gov/pubmed/36901698 http://dx.doi.org/10.3390/ijms24054260

Ejemplares similares

Downregulation of BUD31 Promotes Prostate Cancer Cell Proliferation and Migration via Activation of p-AKT and Vimentin In Vitro
por: Choudhry, Muhammad, et al.
Publicado: (2023)

ARPC1B Is Associated with Lethal Prostate Cancer and Its Inhibition Decreases Cell Invasion and Migration In Vitro
por: Gamallat, Yaser, et al.
Publicado: (2022)

The Association between Cyclin Dependent Kinase 2 Associated Protein 1 (CDK2AP1) and Molecular Subtypes of Lethal Prostate Cancer
por: Gamallat, Yaser, et al.
Publicado: (2022)

The Expression of Proto-Oncogene ETS-Related Gene (ERG) Plays a Central Role in the Oncogenic Mechanism Involved in the Development and Progression of Prostate Cancer
por: Khosh Kish, Ealia, et al.
Publicado: (2022)

Cleavage and Polyadenylation-Specific Factor 4 (CPSF4) Expression Is Associated with Enhanced Prostate Cancer Cell Migration and Cell Cycle Dysregulation, In Vitro
por: Choudhry, Muhammad, et al.
Publicado: (2023)

Glycyl tRNA Synthetase (GARS) Gene Variant Causes Distal Hereditary Motor Neuropathy V
por: Chung, Peter, et al.
Publicado: (2018)

Compound heterozygous mutations in glycyl-tRNA synthetase (GARS) cause mitochondrial respiratory chain dysfunction
por: Nafisinia, Michael, et al.
Publicado: (2017)

Structural Insights into the Polyphyletic Origins of Glycyl tRNA Synthetases
por: Valencia-Sánchez, Marco Igor, et al.
Publicado: (2016)

Mutations in glycyl-tRNA synthetase impair mitochondrial metabolism in neurons
por: Boczonadi, Veronika, et al.
Publicado: (2018)

Neddylation requires glycyl-tRNA synthetase to protect activated E2
por: Mo, Zhongying, et al.
Publicado: (2016)

Associations between Neurological Diseases and Mutations in the Human Glycyl-tRNA Synthetase
por: Vinogradova, Ekaterina S., et al.
Publicado: (2021)

The binding mode of orphan glycyl-tRNA synthetase with tRNA supports the synthetase classification and reveals large domain movements
por: Han, Lu, et al.
Publicado: (2023)

Editorial: The Application of Proteogenomics to Urine Analysis for the Identification of Novel Biomarkers of Prostate Cancer: An Exploratory Study
por: Gamallat, Yaser, et al.
Publicado: (2023)

Mechanism of tRNA recognition by heterotetrameric glycyl-tRNA synthetase from lactic acid bacteria
por: Nagato, Yasuha, et al.
Publicado: (2023)

Saccharomyces cerevisiae Possesses a Stress-Inducible Glycyl-tRNA Synthetase Gene
por: Chen, Shun-Jia, et al.
Publicado: (2012)

Glycyl-tRNA synthetase specifically binds to the poliovirus IRES to activate translation initiation
por: Andreev, Dmitri E., et al.
Publicado: (2012)

Neuropathic Pain Model of Peripheral Neuropathies Mediated by Mutations of Glycyl-tRNA Synthetase
por: Lee, Seo Jin, et al.
Publicado: (2014)

Structural basis of a two-step tRNA recognition mechanism for plastid glycyl-tRNA synthetase
por: Yu, Zhaoli, et al.
Publicado: (2023)

Mutant Glycyl-tRNA Synthetase (Gars) Ameliorates SOD1(G93A) Motor Neuron Degeneration Phenotype but Has Little Affect on Loa Dynein Heavy Chain Mutant Mice
por: Banks, Gareth T., et al.
Publicado: (2009)

CMT2D neuropathy is linked to the neomorphic binding activity of glycyl-tRNA synthetase
por: He, Weiwei, et al.
Publicado: (2015)

Neuropilin 1 sequestration by neuropathogenic mutant glycyl-tRNA synthetase is permissive to vascular homeostasis
por: Sleigh, James N., et al.
Publicado: (2017)

Serrate RNA Effector Molecule (SRRT) Is Associated with Prostate Cancer Progression and Is a Predictor of Poor Prognosis in Lethal Prostate Cancer
por: Gamallat, Yaser, et al.
Publicado: (2023)

Correction: Mutant Glycyl-tRNA Synthetase (Gars) Ameliorates SOD1(G93A) Motor Neuron Degeneration Phenotype but Has Little Affect on Loa Dynein Heavy Chain Mutant Mice
por: Banks, Gareth T., et al.
Publicado: (2009)

Functional Substitution of a Eukaryotic Glycyl-tRNA Synthetase with an Evolutionarily Unrelated Bacterial Cognate Enzyme
por: Chien, Chin-I, et al.
Publicado: (2014)

Compound heterozygous mutations in glycyl-tRNA synthetase are a proposed cause of systemic mitochondrial disease
por: McMillan, Hugh J, et al.
Publicado: (2014)

Early predominant inflammatory myopathy in anti‐glycyl‐tRNA synthetase (EJ) antibody positive antisynthetase syndrome
por: Warner, Robin, et al.
Publicado: (2021)

The Arabidopsis organelle-localized glycyl-tRNA synthetase encoded by EMBRYO DEFECTIVE DEVELOPMENT1 is required for organ patterning
por: Moschopoulos, Alexis, et al.
Publicado: (2012)

Extracellular vesicles derived from macrophages display glycyl‐tRNA synthetase 1 and exhibit anti‐cancer activity
por: Goughnour, Peter C., et al.
Publicado: (2020)

A Rare Case of Anti-glycyl transfer RNA (tRNA) Synthetase Antibody-Related Non-specific Interstitial Pneumonia
por: Khatri Chhetri, Ram Chandra, et al.
Publicado: (2022)

Charcot–Marie–Tooth mutation in glycyl-tRNA synthetase stalls ribosomes in a pre-accommodation state and activates integrated stress response
por: Mendonsa, Samantha, et al.
Publicado: (2021)

Effect of Electroacupuncture on the Expression of Glycyl-tRNA Synthetase and Ultrastructure Changes in Atrophied Rat Peroneus Longus Muscle Induced by Sciatic Nerve Injection Injury
por: Wang, Meng, et al.
Publicado: (2016)

Identification of Putative Drug Targets in Highly Resistant Gram-Negative Bacteria; and Drug Discovery Against Glycyl-tRNA Synthetase as a New Target
por: Fereshteh, Sepideh, et al.
Publicado: (2023)

THE EFFECT OF THE HYDROGEN ION CONCENTRATION ON THE RATE OF HYDROLYSIS OF GLYCYL GLYCINE, GLYCYL LEUCINE, GLYCYL ALANINE, GLYCYL ASPARAGINE, GLYCYL ASPARTIC ACID, AND BIURET BASE BY EREPSIN
por: Northrop, John H., et al.
Publicado: (1928)

Peculiarities of aminoacyl-tRNA synthetases from trypanosomatids
por: Parrot, Camila, et al.
Publicado: (2021)

A biosynthetic pathway to aromatic amines that uses glycyl-tRNA as nitrogen donor
por: Daniels, Page N., et al.
Publicado: (2022)

Long-term clinical course of anti-glycyl tRNA synthetase (anti-EJ) antibody-related interstitial lung disease pathologically proven by surgical lung biopsy
por: Sasano, Hajime, et al.
Publicado: (2016)

Bacterial Aspartyl-tRNA Synthetase Has Glutamyl-tRNA Synthetase Activity
por: Rathnayake, Udumbara M., et al.
Publicado: (2019)

Aminoacyl-tRNA synthetases of the multi-tRNA synthetase complex and their role in tumorigenesis
por: Khan, Krishnendu, et al.
Publicado: (2022)

Large, Nested Variant of Urothelial Carcinoma Is Enriched with Activating Mutations in Fibroblast Growth Factor Receptor-3 among Other Targetable Mutations
por: Gamallat, Yaser, et al.
Publicado: (2023)

Aminoacyl-tRNA synthetases
por: Rubio Gomez, Miguel Angel, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_cbjgk1sd5aere5q2bm78gksemd