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Risk Factors for Mortality of Hospitalized Adult Patients with COVID-19 Pneumonia: A Two-Year Cohort Study in a Private Tertiary Care Center in Mexico
During the COVID-19 pandemic, the high prevalence of comorbidities and the disparities between the public and private health subsystems in Mexico substantially contributed to the severe impact of the disease. The objective of this study was to evaluate and compare the risk factors at admission for i...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10001871/ https://www.ncbi.nlm.nih.gov/pubmed/36901460 http://dx.doi.org/10.3390/ijerph20054450 |
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author | López-Pérez, Carlos Axel Santa Cruz-Pavlovich, Francisco J. Montiel-Cortés, Juan Eduardo Núñez-Muratalla, Adriana Morán-González, Ruth Bibani Villanueva-Gaona, Ricardo Franco-Mojica, Xochitl Moreno-Sandoval, Denisse Gabriela González-Bañuelos, Joselyn Anacaren López-Pérez, Alan Ulises Flores-González, Marily Grijalva-Ruiz, Cristina Valdez-Mendoza, Edna Daniela González-Lucano, Luis Renee López-Zendejas, Martín |
author_facet | López-Pérez, Carlos Axel Santa Cruz-Pavlovich, Francisco J. Montiel-Cortés, Juan Eduardo Núñez-Muratalla, Adriana Morán-González, Ruth Bibani Villanueva-Gaona, Ricardo Franco-Mojica, Xochitl Moreno-Sandoval, Denisse Gabriela González-Bañuelos, Joselyn Anacaren López-Pérez, Alan Ulises Flores-González, Marily Grijalva-Ruiz, Cristina Valdez-Mendoza, Edna Daniela González-Lucano, Luis Renee López-Zendejas, Martín |
author_sort | López-Pérez, Carlos Axel |
collection | PubMed |
description | During the COVID-19 pandemic, the high prevalence of comorbidities and the disparities between the public and private health subsystems in Mexico substantially contributed to the severe impact of the disease. The objective of this study was to evaluate and compare the risk factors at admission for in-hospital mortality of patients with COVID-19. A 2-year retrospective cohort study of hospitalized adult patients with COVID-19 pneumonia was conducted at a private tertiary care center. The study population consisted of 1258 patients with a median age of 56 ± 16.5 years, of whom 1093 recovered (86.8%) and 165 died (13.1%). In the univariate analysis, older age (p < 0.001), comorbidities such as hypertension (p < 0.001) and diabetes (p < 0.001), signs and symptoms of respiratory distress, and markers of acute inflammatory response were significantly more frequent in non-survivors. The multivariate analysis showed that older age (p < 0.001), the presence of cyanosis (p = 0.005), and previous myocardial infarction (p = 0.032) were independent predictors of mortality. In the studied cohort, the risk factors present at admission associated with increased mortality were older age, cyanosis, and a previous myocardial infarction, which can be used as valuable predictors for patients’ outcomes. To our knowledge, this is the first study analyzing predictors of mortality in COVID-19 patients attended in a private tertiary hospital in Mexico. |
format | Online Article Text |
id | pubmed-10001871 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-100018712023-03-11 Risk Factors for Mortality of Hospitalized Adult Patients with COVID-19 Pneumonia: A Two-Year Cohort Study in a Private Tertiary Care Center in Mexico López-Pérez, Carlos Axel Santa Cruz-Pavlovich, Francisco J. Montiel-Cortés, Juan Eduardo Núñez-Muratalla, Adriana Morán-González, Ruth Bibani Villanueva-Gaona, Ricardo Franco-Mojica, Xochitl Moreno-Sandoval, Denisse Gabriela González-Bañuelos, Joselyn Anacaren López-Pérez, Alan Ulises Flores-González, Marily Grijalva-Ruiz, Cristina Valdez-Mendoza, Edna Daniela González-Lucano, Luis Renee López-Zendejas, Martín Int J Environ Res Public Health Article During the COVID-19 pandemic, the high prevalence of comorbidities and the disparities between the public and private health subsystems in Mexico substantially contributed to the severe impact of the disease. The objective of this study was to evaluate and compare the risk factors at admission for in-hospital mortality of patients with COVID-19. A 2-year retrospective cohort study of hospitalized adult patients with COVID-19 pneumonia was conducted at a private tertiary care center. The study population consisted of 1258 patients with a median age of 56 ± 16.5 years, of whom 1093 recovered (86.8%) and 165 died (13.1%). In the univariate analysis, older age (p < 0.001), comorbidities such as hypertension (p < 0.001) and diabetes (p < 0.001), signs and symptoms of respiratory distress, and markers of acute inflammatory response were significantly more frequent in non-survivors. The multivariate analysis showed that older age (p < 0.001), the presence of cyanosis (p = 0.005), and previous myocardial infarction (p = 0.032) were independent predictors of mortality. In the studied cohort, the risk factors present at admission associated with increased mortality were older age, cyanosis, and a previous myocardial infarction, which can be used as valuable predictors for patients’ outcomes. To our knowledge, this is the first study analyzing predictors of mortality in COVID-19 patients attended in a private tertiary hospital in Mexico. MDPI 2023-03-02 /pmc/articles/PMC10001871/ /pubmed/36901460 http://dx.doi.org/10.3390/ijerph20054450 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article López-Pérez, Carlos Axel Santa Cruz-Pavlovich, Francisco J. Montiel-Cortés, Juan Eduardo Núñez-Muratalla, Adriana Morán-González, Ruth Bibani Villanueva-Gaona, Ricardo Franco-Mojica, Xochitl Moreno-Sandoval, Denisse Gabriela González-Bañuelos, Joselyn Anacaren López-Pérez, Alan Ulises Flores-González, Marily Grijalva-Ruiz, Cristina Valdez-Mendoza, Edna Daniela González-Lucano, Luis Renee López-Zendejas, Martín Risk Factors for Mortality of Hospitalized Adult Patients with COVID-19 Pneumonia: A Two-Year Cohort Study in a Private Tertiary Care Center in Mexico |
title | Risk Factors for Mortality of Hospitalized Adult Patients with COVID-19 Pneumonia: A Two-Year Cohort Study in a Private Tertiary Care Center in Mexico |
title_full | Risk Factors for Mortality of Hospitalized Adult Patients with COVID-19 Pneumonia: A Two-Year Cohort Study in a Private Tertiary Care Center in Mexico |
title_fullStr | Risk Factors for Mortality of Hospitalized Adult Patients with COVID-19 Pneumonia: A Two-Year Cohort Study in a Private Tertiary Care Center in Mexico |
title_full_unstemmed | Risk Factors for Mortality of Hospitalized Adult Patients with COVID-19 Pneumonia: A Two-Year Cohort Study in a Private Tertiary Care Center in Mexico |
title_short | Risk Factors for Mortality of Hospitalized Adult Patients with COVID-19 Pneumonia: A Two-Year Cohort Study in a Private Tertiary Care Center in Mexico |
title_sort | risk factors for mortality of hospitalized adult patients with covid-19 pneumonia: a two-year cohort study in a private tertiary care center in mexico |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10001871/ https://www.ncbi.nlm.nih.gov/pubmed/36901460 http://dx.doi.org/10.3390/ijerph20054450 |
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