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Enhancing the Breast Histopathology Image Analysis for Cancer Detection Using Variational Autoencoder

A breast tissue biopsy is performed to identify the nature of a tumour, as it can be either cancerous or benign. The first implementations involved the use of machine learning algorithms. Random Forest and Support Vector Machine (SVM) were used to classify the input histopathological images into whe...

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Autores principales: Guleria, Harsh Vardhan, Luqmani, Ali Mazhar, Kothari, Harsh Devendra, Phukan, Priyanshu, Patil, Shruti, Pareek, Preksha, Kotecha, Ketan, Abraham, Ajith, Gabralla, Lubna Abdelkareim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002012/
https://www.ncbi.nlm.nih.gov/pubmed/36901255
http://dx.doi.org/10.3390/ijerph20054244
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author Guleria, Harsh Vardhan
Luqmani, Ali Mazhar
Kothari, Harsh Devendra
Phukan, Priyanshu
Patil, Shruti
Pareek, Preksha
Kotecha, Ketan
Abraham, Ajith
Gabralla, Lubna Abdelkareim
author_facet Guleria, Harsh Vardhan
Luqmani, Ali Mazhar
Kothari, Harsh Devendra
Phukan, Priyanshu
Patil, Shruti
Pareek, Preksha
Kotecha, Ketan
Abraham, Ajith
Gabralla, Lubna Abdelkareim
author_sort Guleria, Harsh Vardhan
collection PubMed
description A breast tissue biopsy is performed to identify the nature of a tumour, as it can be either cancerous or benign. The first implementations involved the use of machine learning algorithms. Random Forest and Support Vector Machine (SVM) were used to classify the input histopathological images into whether they were cancerous or non-cancerous. The implementations continued to provide promising results, and then Artificial Neural Networks (ANNs) were applied for this purpose. We propose an approach for reconstructing the images using a Variational Autoencoder (VAE) and the Denoising Variational Autoencoder (DVAE) and then use a Convolutional Neural Network (CNN) model. Afterwards, we predicted whether the input image was cancerous or non-cancerous. Our implementation provides predictions with 73% accuracy, which is greater than the results produced by our custom-built CNN on our dataset. The proposed architecture will prove to be a new field of research and a new area to be explored in the field of computer vision using CNN and Generative Modelling since it incorporates reconstructions of the original input images and provides predictions on them thereafter.
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spelling pubmed-100020122023-03-11 Enhancing the Breast Histopathology Image Analysis for Cancer Detection Using Variational Autoencoder Guleria, Harsh Vardhan Luqmani, Ali Mazhar Kothari, Harsh Devendra Phukan, Priyanshu Patil, Shruti Pareek, Preksha Kotecha, Ketan Abraham, Ajith Gabralla, Lubna Abdelkareim Int J Environ Res Public Health Article A breast tissue biopsy is performed to identify the nature of a tumour, as it can be either cancerous or benign. The first implementations involved the use of machine learning algorithms. Random Forest and Support Vector Machine (SVM) were used to classify the input histopathological images into whether they were cancerous or non-cancerous. The implementations continued to provide promising results, and then Artificial Neural Networks (ANNs) were applied for this purpose. We propose an approach for reconstructing the images using a Variational Autoencoder (VAE) and the Denoising Variational Autoencoder (DVAE) and then use a Convolutional Neural Network (CNN) model. Afterwards, we predicted whether the input image was cancerous or non-cancerous. Our implementation provides predictions with 73% accuracy, which is greater than the results produced by our custom-built CNN on our dataset. The proposed architecture will prove to be a new field of research and a new area to be explored in the field of computer vision using CNN and Generative Modelling since it incorporates reconstructions of the original input images and provides predictions on them thereafter. MDPI 2023-02-27 /pmc/articles/PMC10002012/ /pubmed/36901255 http://dx.doi.org/10.3390/ijerph20054244 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Guleria, Harsh Vardhan
Luqmani, Ali Mazhar
Kothari, Harsh Devendra
Phukan, Priyanshu
Patil, Shruti
Pareek, Preksha
Kotecha, Ketan
Abraham, Ajith
Gabralla, Lubna Abdelkareim
Enhancing the Breast Histopathology Image Analysis for Cancer Detection Using Variational Autoencoder
title Enhancing the Breast Histopathology Image Analysis for Cancer Detection Using Variational Autoencoder
title_full Enhancing the Breast Histopathology Image Analysis for Cancer Detection Using Variational Autoencoder
title_fullStr Enhancing the Breast Histopathology Image Analysis for Cancer Detection Using Variational Autoencoder
title_full_unstemmed Enhancing the Breast Histopathology Image Analysis for Cancer Detection Using Variational Autoencoder
title_short Enhancing the Breast Histopathology Image Analysis for Cancer Detection Using Variational Autoencoder
title_sort enhancing the breast histopathology image analysis for cancer detection using variational autoencoder
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002012/
https://www.ncbi.nlm.nih.gov/pubmed/36901255
http://dx.doi.org/10.3390/ijerph20054244
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