Identifying Drug Candidates for COVID-19 with Large-Scale Drug Screening

Papain-like protease (PL(pro)) is critical to COVID-19 infection. Therefore, it is a significant target protein for drug development. We virtually screened a 26,193 compound library against the PL(pro) of SARS-CoV-2 and identified several drug candidates with convincing binding affinities. The three...

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Detalles Bibliográficos
Autores principales: Wu, Yifei, Pegan, Scott D., Crich, David, Lou, Lei, Mullininx, Lauren Nicole, Starling, Edward B., Booth, Carson, Chishom, Andrew Edward, Chang, Kuan Y., Xie, Zhong-Ru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002104/
https://www.ncbi.nlm.nih.gov/pubmed/36901828
http://dx.doi.org/10.3390/ijms24054397

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002104/
https://www.ncbi.nlm.nih.gov/pubmed/36901828
http://dx.doi.org/10.3390/ijms24054397

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