Cargando…

Purification of PaTx-II from the Venom of the Australian King Brown Snake and Characterization of Its Antimicrobial and Wound Healing Activities

Infections caused by multi-drug-resistant (MDR) bacteria are a global threat to human health. As venoms are the source of biochemically diverse bioactive proteins and peptides, we investigated the antimicrobial activity and murine skin infection model-based wound healing efficacy of a 13 kDa protein...

Descripción completa

Detalles Bibliográficos
Autores principales:	Samy, Ramar Perumal, Mackessy, Stephen P., Jeyasankar, Alagarmalai, Ponraj, Mano Ranjana, Franco, Octavio Luiz, Cooper, Matthew A., Kandasamy, Matheswaran, Mohanta, Tapan Kumar, Bhagavathsingh, Jebasingh, Vaiyapuri, Sakthivel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002107/ https://www.ncbi.nlm.nih.gov/pubmed/36901790 http://dx.doi.org/10.3390/ijms24054359

Ejemplares similares

Design of novel pyrimidine based remdesivir analogues with dual target specificity for SARS CoV-2: A computational approach
por: Dinesh, T.V., et al.
Publicado: (2023)

Therapeutic application of natural inhibitors against snake venom phospholipase A(2)
por: Perumal Samy, Ramar, et al.
Publicado: (2012)

Wound Healing Activity and Mechanisms of Action of an Antibacterial Protein from the Venom of the Eastern Diamondback Rattlesnake (Crotalus adamanteus)
por: Samy, Ramar Perumal, et al.
Publicado: (2014)

Copper(II)-Bis-Cyclen Intercalated Graphene Oxide as an Efficient Two-Dimensional Nanocomposite Material for Copper-Catalyzed Azide–Alkyne Cycloaddition Reaction
por: Samuel, Angel Green, et al.
Publicado: (2022)

Presynaptic Proteins as Markers of the Neurotoxic Activity of BmjeTX-I and BmjeTX-II Toxins from Bothrops marajoensis (Marajó Lancehead) Snake Venom
por: Lisboa, Antonio, et al.
Publicado: (2016)

Mithridates VI Eupator king of Pontus and the venomous snakes
por: Valle, Guido, et al.
Publicado: (2017)

Mechanisms underpinning the permanent muscle damage induced by snake venom metalloprotease
por: Williams, Harry F., et al.
Publicado: (2019)

Molecular basis for prey relocation in viperid snakes
por: Saviola, Anthony J, et al.
Publicado: (2013)

Ashes to eye: A skilled snake handler’s experience with ophthalmic envenomation
por: Williams, Harry F., et al.
Publicado: (2023)

Tris-(2-aminoethyl)amine-Intercalated Graphene Oxide as an Efficient 2D Material for Cerium-Ion Fluorescent Sensor Applications
por: Elsie, Stephena, et al.
Publicado: (2019)

Therapeutic Potential of Plants as Anti-microbials for Drug Discovery
por: Perumal Samy, Ramar, et al.
Publicado: (2010)

Editorial: Burkholderia spp.-transmission, pathogenesis, host-pathogen interaction, prevention and treatment
por: Buroni, Silvia, et al.
Publicado: (2023)

Polyaza functionalized graphene oxide nanomaterial based sensor for Escherichia coli detection in water matrices
por: Rose, Lina, et al.
Publicado: (2021)

First Insights into the Venom Composition of Two Ecuadorian Coral Snakes
por: Hernández-Altamirano, Josselin A., et al.
Publicado: (2022)

Pilot Study with regard to the Wound Healing Activity of Protein from Calotropis procera (Ait.) R. Br.
por: Perumal Samy, Ramar, et al.
Publicado: (2012)

An Unnecessary Russell’s Viper Bite on the Tongue Due to Live Snake Worship and Dangerous First Aid Emphasise the Urgent Need for Stringent Policies
por: Senthilkumaran, Subramanian, et al.
Publicado: (2022)

Unmasking Snake Venom of Bothrops leucurus: Purification and Pharmacological and Structural Characterization of New PLA(2) Bleu TX-III
por: Marangoni, Fábio André, et al.
Publicado: (2013)

Role of accelerated segment switch in exons to alter targeting (ASSET) in the molecular evolution of snake venom proteins
por: Doley, Robin, et al.
Publicado: (2009)

Venomous snakebites: Rapid action saves lives—A multifaceted community education programme increases awareness about snakes and snakebites among the rural population of Tamil Nadu, India
por: Samuel, Stephen Paul, et al.
Publicado: (2020)

Chemical Modifications of PhTX-I Myotoxin from Porthidium hyoprora Snake Venom: Effects on Structural, Enzymatic, and Pharmacological Properties
por: Huancahuire-Vega, Salomón, et al.
Publicado: (2013)

A compilation of Bioactive Compounds from Ayurveda
por: Samy, Ramar Perumal, et al.
Publicado: (2008)

Evaluation of Aromatic Plants and Compounds Used to Fight Multidrug Resistant Infections
por: Perumal Samy, Ramar, et al.
Publicado: (2013)

Linear B-cell epitopes in BthTX-I, BthTX-II and BthA-I, phospholipase A(2's )from Bothrops jararacussu snake venom, recognized by therapeutically neutralizing commercial horse antivenom
por: De-Simone, Salvatore, et al.
Publicado: (2014)

Intramuscular Bleeding and Formation of Microthrombi during Skeletal Muscle Damage Caused by a Snake Venom Metalloprotease and a Cardiotoxin
por: Sonavane, Medha, et al.
Publicado: (2023)

Biochemical, Pharmacological, and Structural Characterization of New Basic P L A (2) Bbil-TX from Bothriopsis bilineata Snake Venom
por: Corasolla Carregari, Victor, et al.
Publicado: (2013)

The venom gland transcriptome of the Desert Massasauga Rattlesnake (Sistrurus catenatus edwardsii): towards an understanding of venom composition among advanced snakes (Superfamily Colubroidea)
por: Pahari, Susanta, et al.
Publicado: (2007)

Physiological demands and signaling associated with snake venom production and storage illustrated by transcriptional analyses of venom glands
por: Perry, Blair W., et al.
Publicado: (2020)

Esterilidad femenina Dx. y Tx. /
por: Jiménez Jácome, José Alfredo
Publicado: (1987)

King Cobra and snakebite envenomation: on the natural history, human-snake relationship and medical importance of Ophiophagus hannah
por: Tan, Choo Hock, et al.
Publicado: (2022)

Melioidosis: Clinical impact and public health threat in the tropics
por: Perumal Samy, Ramar, et al.
Publicado: (2017)

Cytotoxic and pro-apoptotic action of MjTX-I, a phospholipase A2 isolated from Bothrops moojeni snake venom, towards leukemic cells
por: Benati, Rogério Bodini, et al.
Publicado: (2018)

Degradation kinetics of α‐conotoxin TxID
por: Xu, Pan, et al.
Publicado: (2019)

Biochemical Characterization and Pharmacological Properties of New Basic PLA(2) BrTX-I Isolated from Bothrops roedingeri (Roedinger's Lancehead) Mertens, 1942, Snake Venom
por: Gomes Heleno, Mauricio Aurelio, et al.
Publicado: (2013)

PhTX-II a Basic Myotoxic Phospholipase A(2) from Porthidium hyoprora Snake Venom, Pharmacological Characterization and Amino Acid Sequence by Mass Spectrometry
por: Huancahuire-Vega, Salomón, et al.
Publicado: (2014)

Antitumor potential of the myotoxin BthTX-I from Bothrops jararacussu snake venom: evaluation of cell cycle alterations and death mechanisms induced in tumor cell lines
por: Prinholato da Silva, Cássio, et al.
Publicado: (2015)

The CSF of normal H-Tx rats promotes neuronal differentiation from neurospheres but CSF of hydrocephalic H-Tx rats does not
por: González, César, et al.
Publicado: (2006)

Selective sorption of PAHs from TX100 solution by resin SP850: effects of TX100 concentrations and PAHs solubility
por: Zeng, Yaxiong, et al.
Publicado: (2021)

Single-Cell Heterogeneity in Snake Venom Expression Is Hardwired by Co-Option of Regulators from Progressively Activated Pathways
por: Westfall, Aundrea K, et al.
Publicado: (2023)

RNA-seq and high-definition mass spectrometry reveal the complex and divergent venoms of two rear-fanged colubrid snakes
por: McGivern, James J, et al.
Publicado: (2014)

Suppression of Cytotoxic T Cell Functions and Decreased Levels of Tissue-Resident Memory T Cells during H5N1 Infection
por: Kandasamy, Matheswaran, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_q8sotriifeu096jmtkjr0f3ege