Cargando…

Hospital Length of Stay and Surgery among European Children with Rare Structural Congenital Anomalies—A Population-Based Data Linkage Study

Little is known about morbidity for children with rare structural congenital anomalies. This European, population-based data-linkage cohort study analysed data on hospitalisations and surgical procedures for 5948 children born 1995–2014 with 18 rare structural congenital anomalies from nine EUROCAT...

Descripción completa

Detalles Bibliográficos
Autores principales: Garne, Ester, Tan, Joachim, Damkjaer, Mads, Ballardini, Elisa, Cavero-Carbonell, Clara, Coi, Alessio, Garcia-Villodre, Laura, Gissler, Mika, Given, Joanne, Heino, Anna, Jordan, Sue, Limb, Elizabeth, Loane, Maria, Neville, Amanda J., Pierini, Anna, Rissmann, Anke, Tucker, David, Urhoj, Stine Kjaer, Morris, Joan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002318/
https://www.ncbi.nlm.nih.gov/pubmed/36901396
http://dx.doi.org/10.3390/ijerph20054387
_version_ 1784904360921137152
author Garne, Ester
Tan, Joachim
Damkjaer, Mads
Ballardini, Elisa
Cavero-Carbonell, Clara
Coi, Alessio
Garcia-Villodre, Laura
Gissler, Mika
Given, Joanne
Heino, Anna
Jordan, Sue
Limb, Elizabeth
Loane, Maria
Neville, Amanda J.
Pierini, Anna
Rissmann, Anke
Tucker, David
Urhoj, Stine Kjaer
Morris, Joan
author_facet Garne, Ester
Tan, Joachim
Damkjaer, Mads
Ballardini, Elisa
Cavero-Carbonell, Clara
Coi, Alessio
Garcia-Villodre, Laura
Gissler, Mika
Given, Joanne
Heino, Anna
Jordan, Sue
Limb, Elizabeth
Loane, Maria
Neville, Amanda J.
Pierini, Anna
Rissmann, Anke
Tucker, David
Urhoj, Stine Kjaer
Morris, Joan
author_sort Garne, Ester
collection PubMed
description Little is known about morbidity for children with rare structural congenital anomalies. This European, population-based data-linkage cohort study analysed data on hospitalisations and surgical procedures for 5948 children born 1995–2014 with 18 rare structural congenital anomalies from nine EUROCAT registries in five countries. In the first year of life, the median length of stay (LOS) ranged from 3.5 days (anotia) to 53.8 days (atresia of bile ducts). Generally, children with gastrointestinal anomalies, bladder anomalies and Prune-Belly had the longest LOS. At ages 1–4, the median LOS per year was ≤3 days for most anomalies. The proportion of children having surgery before age 5 years ranged from 40% to 100%. The median number of surgical procedures for those under 5 years was two or more for 14 of the 18 anomalies and the highest for children with Prune-Belly at 7.4 (95% CI 2.5–12.3). The median age at first surgery for children with atresia of bile ducts was 8.4 weeks (95% CI 7.6–9.2) which is older than international recommendations. Results from the subset of registries with data up to 10 years of age showed that the need for hospitalisations and surgery continued. The burden of disease in early childhood is high for children with rare structural congenital anomalies.
format Online
Article
Text
id pubmed-10002318
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-100023182023-03-11 Hospital Length of Stay and Surgery among European Children with Rare Structural Congenital Anomalies—A Population-Based Data Linkage Study Garne, Ester Tan, Joachim Damkjaer, Mads Ballardini, Elisa Cavero-Carbonell, Clara Coi, Alessio Garcia-Villodre, Laura Gissler, Mika Given, Joanne Heino, Anna Jordan, Sue Limb, Elizabeth Loane, Maria Neville, Amanda J. Pierini, Anna Rissmann, Anke Tucker, David Urhoj, Stine Kjaer Morris, Joan Int J Environ Res Public Health Article Little is known about morbidity for children with rare structural congenital anomalies. This European, population-based data-linkage cohort study analysed data on hospitalisations and surgical procedures for 5948 children born 1995–2014 with 18 rare structural congenital anomalies from nine EUROCAT registries in five countries. In the first year of life, the median length of stay (LOS) ranged from 3.5 days (anotia) to 53.8 days (atresia of bile ducts). Generally, children with gastrointestinal anomalies, bladder anomalies and Prune-Belly had the longest LOS. At ages 1–4, the median LOS per year was ≤3 days for most anomalies. The proportion of children having surgery before age 5 years ranged from 40% to 100%. The median number of surgical procedures for those under 5 years was two or more for 14 of the 18 anomalies and the highest for children with Prune-Belly at 7.4 (95% CI 2.5–12.3). The median age at first surgery for children with atresia of bile ducts was 8.4 weeks (95% CI 7.6–9.2) which is older than international recommendations. Results from the subset of registries with data up to 10 years of age showed that the need for hospitalisations and surgery continued. The burden of disease in early childhood is high for children with rare structural congenital anomalies. MDPI 2023-03-01 /pmc/articles/PMC10002318/ /pubmed/36901396 http://dx.doi.org/10.3390/ijerph20054387 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Garne, Ester
Tan, Joachim
Damkjaer, Mads
Ballardini, Elisa
Cavero-Carbonell, Clara
Coi, Alessio
Garcia-Villodre, Laura
Gissler, Mika
Given, Joanne
Heino, Anna
Jordan, Sue
Limb, Elizabeth
Loane, Maria
Neville, Amanda J.
Pierini, Anna
Rissmann, Anke
Tucker, David
Urhoj, Stine Kjaer
Morris, Joan
Hospital Length of Stay and Surgery among European Children with Rare Structural Congenital Anomalies—A Population-Based Data Linkage Study
title Hospital Length of Stay and Surgery among European Children with Rare Structural Congenital Anomalies—A Population-Based Data Linkage Study
title_full Hospital Length of Stay and Surgery among European Children with Rare Structural Congenital Anomalies—A Population-Based Data Linkage Study
title_fullStr Hospital Length of Stay and Surgery among European Children with Rare Structural Congenital Anomalies—A Population-Based Data Linkage Study
title_full_unstemmed Hospital Length of Stay and Surgery among European Children with Rare Structural Congenital Anomalies—A Population-Based Data Linkage Study
title_short Hospital Length of Stay and Surgery among European Children with Rare Structural Congenital Anomalies—A Population-Based Data Linkage Study
title_sort hospital length of stay and surgery among european children with rare structural congenital anomalies—a population-based data linkage study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002318/
https://www.ncbi.nlm.nih.gov/pubmed/36901396
http://dx.doi.org/10.3390/ijerph20054387
work_keys_str_mv AT garneester hospitallengthofstayandsurgeryamongeuropeanchildrenwithrarestructuralcongenitalanomaliesapopulationbaseddatalinkagestudy
AT tanjoachim hospitallengthofstayandsurgeryamongeuropeanchildrenwithrarestructuralcongenitalanomaliesapopulationbaseddatalinkagestudy
AT damkjaermads hospitallengthofstayandsurgeryamongeuropeanchildrenwithrarestructuralcongenitalanomaliesapopulationbaseddatalinkagestudy
AT ballardinielisa hospitallengthofstayandsurgeryamongeuropeanchildrenwithrarestructuralcongenitalanomaliesapopulationbaseddatalinkagestudy
AT caverocarbonellclara hospitallengthofstayandsurgeryamongeuropeanchildrenwithrarestructuralcongenitalanomaliesapopulationbaseddatalinkagestudy
AT coialessio hospitallengthofstayandsurgeryamongeuropeanchildrenwithrarestructuralcongenitalanomaliesapopulationbaseddatalinkagestudy
AT garciavillodrelaura hospitallengthofstayandsurgeryamongeuropeanchildrenwithrarestructuralcongenitalanomaliesapopulationbaseddatalinkagestudy
AT gisslermika hospitallengthofstayandsurgeryamongeuropeanchildrenwithrarestructuralcongenitalanomaliesapopulationbaseddatalinkagestudy
AT givenjoanne hospitallengthofstayandsurgeryamongeuropeanchildrenwithrarestructuralcongenitalanomaliesapopulationbaseddatalinkagestudy
AT heinoanna hospitallengthofstayandsurgeryamongeuropeanchildrenwithrarestructuralcongenitalanomaliesapopulationbaseddatalinkagestudy
AT jordansue hospitallengthofstayandsurgeryamongeuropeanchildrenwithrarestructuralcongenitalanomaliesapopulationbaseddatalinkagestudy
AT limbelizabeth hospitallengthofstayandsurgeryamongeuropeanchildrenwithrarestructuralcongenitalanomaliesapopulationbaseddatalinkagestudy
AT loanemaria hospitallengthofstayandsurgeryamongeuropeanchildrenwithrarestructuralcongenitalanomaliesapopulationbaseddatalinkagestudy
AT nevilleamandaj hospitallengthofstayandsurgeryamongeuropeanchildrenwithrarestructuralcongenitalanomaliesapopulationbaseddatalinkagestudy
AT pierinianna hospitallengthofstayandsurgeryamongeuropeanchildrenwithrarestructuralcongenitalanomaliesapopulationbaseddatalinkagestudy
AT rissmannanke hospitallengthofstayandsurgeryamongeuropeanchildrenwithrarestructuralcongenitalanomaliesapopulationbaseddatalinkagestudy
AT tuckerdavid hospitallengthofstayandsurgeryamongeuropeanchildrenwithrarestructuralcongenitalanomaliesapopulationbaseddatalinkagestudy
AT urhojstinekjaer hospitallengthofstayandsurgeryamongeuropeanchildrenwithrarestructuralcongenitalanomaliesapopulationbaseddatalinkagestudy
AT morrisjoan hospitallengthofstayandsurgeryamongeuropeanchildrenwithrarestructuralcongenitalanomaliesapopulationbaseddatalinkagestudy