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Hospital Length of Stay and Surgery among European Children with Rare Structural Congenital Anomalies—A Population-Based Data Linkage Study
Little is known about morbidity for children with rare structural congenital anomalies. This European, population-based data-linkage cohort study analysed data on hospitalisations and surgical procedures for 5948 children born 1995–2014 with 18 rare structural congenital anomalies from nine EUROCAT...
Autores principales: | , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002318/ https://www.ncbi.nlm.nih.gov/pubmed/36901396 http://dx.doi.org/10.3390/ijerph20054387 |
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author | Garne, Ester Tan, Joachim Damkjaer, Mads Ballardini, Elisa Cavero-Carbonell, Clara Coi, Alessio Garcia-Villodre, Laura Gissler, Mika Given, Joanne Heino, Anna Jordan, Sue Limb, Elizabeth Loane, Maria Neville, Amanda J. Pierini, Anna Rissmann, Anke Tucker, David Urhoj, Stine Kjaer Morris, Joan |
author_facet | Garne, Ester Tan, Joachim Damkjaer, Mads Ballardini, Elisa Cavero-Carbonell, Clara Coi, Alessio Garcia-Villodre, Laura Gissler, Mika Given, Joanne Heino, Anna Jordan, Sue Limb, Elizabeth Loane, Maria Neville, Amanda J. Pierini, Anna Rissmann, Anke Tucker, David Urhoj, Stine Kjaer Morris, Joan |
author_sort | Garne, Ester |
collection | PubMed |
description | Little is known about morbidity for children with rare structural congenital anomalies. This European, population-based data-linkage cohort study analysed data on hospitalisations and surgical procedures for 5948 children born 1995–2014 with 18 rare structural congenital anomalies from nine EUROCAT registries in five countries. In the first year of life, the median length of stay (LOS) ranged from 3.5 days (anotia) to 53.8 days (atresia of bile ducts). Generally, children with gastrointestinal anomalies, bladder anomalies and Prune-Belly had the longest LOS. At ages 1–4, the median LOS per year was ≤3 days for most anomalies. The proportion of children having surgery before age 5 years ranged from 40% to 100%. The median number of surgical procedures for those under 5 years was two or more for 14 of the 18 anomalies and the highest for children with Prune-Belly at 7.4 (95% CI 2.5–12.3). The median age at first surgery for children with atresia of bile ducts was 8.4 weeks (95% CI 7.6–9.2) which is older than international recommendations. Results from the subset of registries with data up to 10 years of age showed that the need for hospitalisations and surgery continued. The burden of disease in early childhood is high for children with rare structural congenital anomalies. |
format | Online Article Text |
id | pubmed-10002318 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-100023182023-03-11 Hospital Length of Stay and Surgery among European Children with Rare Structural Congenital Anomalies—A Population-Based Data Linkage Study Garne, Ester Tan, Joachim Damkjaer, Mads Ballardini, Elisa Cavero-Carbonell, Clara Coi, Alessio Garcia-Villodre, Laura Gissler, Mika Given, Joanne Heino, Anna Jordan, Sue Limb, Elizabeth Loane, Maria Neville, Amanda J. Pierini, Anna Rissmann, Anke Tucker, David Urhoj, Stine Kjaer Morris, Joan Int J Environ Res Public Health Article Little is known about morbidity for children with rare structural congenital anomalies. This European, population-based data-linkage cohort study analysed data on hospitalisations and surgical procedures for 5948 children born 1995–2014 with 18 rare structural congenital anomalies from nine EUROCAT registries in five countries. In the first year of life, the median length of stay (LOS) ranged from 3.5 days (anotia) to 53.8 days (atresia of bile ducts). Generally, children with gastrointestinal anomalies, bladder anomalies and Prune-Belly had the longest LOS. At ages 1–4, the median LOS per year was ≤3 days for most anomalies. The proportion of children having surgery before age 5 years ranged from 40% to 100%. The median number of surgical procedures for those under 5 years was two or more for 14 of the 18 anomalies and the highest for children with Prune-Belly at 7.4 (95% CI 2.5–12.3). The median age at first surgery for children with atresia of bile ducts was 8.4 weeks (95% CI 7.6–9.2) which is older than international recommendations. Results from the subset of registries with data up to 10 years of age showed that the need for hospitalisations and surgery continued. The burden of disease in early childhood is high for children with rare structural congenital anomalies. MDPI 2023-03-01 /pmc/articles/PMC10002318/ /pubmed/36901396 http://dx.doi.org/10.3390/ijerph20054387 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Garne, Ester Tan, Joachim Damkjaer, Mads Ballardini, Elisa Cavero-Carbonell, Clara Coi, Alessio Garcia-Villodre, Laura Gissler, Mika Given, Joanne Heino, Anna Jordan, Sue Limb, Elizabeth Loane, Maria Neville, Amanda J. Pierini, Anna Rissmann, Anke Tucker, David Urhoj, Stine Kjaer Morris, Joan Hospital Length of Stay and Surgery among European Children with Rare Structural Congenital Anomalies—A Population-Based Data Linkage Study |
title | Hospital Length of Stay and Surgery among European Children with Rare Structural Congenital Anomalies—A Population-Based Data Linkage Study |
title_full | Hospital Length of Stay and Surgery among European Children with Rare Structural Congenital Anomalies—A Population-Based Data Linkage Study |
title_fullStr | Hospital Length of Stay and Surgery among European Children with Rare Structural Congenital Anomalies—A Population-Based Data Linkage Study |
title_full_unstemmed | Hospital Length of Stay and Surgery among European Children with Rare Structural Congenital Anomalies—A Population-Based Data Linkage Study |
title_short | Hospital Length of Stay and Surgery among European Children with Rare Structural Congenital Anomalies—A Population-Based Data Linkage Study |
title_sort | hospital length of stay and surgery among european children with rare structural congenital anomalies—a population-based data linkage study |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002318/ https://www.ncbi.nlm.nih.gov/pubmed/36901396 http://dx.doi.org/10.3390/ijerph20054387 |
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