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Malonyl-CoA Accumulation as a Compensatory Cytoprotective Mechanism in Cardiac Cells in Response to 7-Ketocholesterol-Induced Growth Retardation

The major oxidized product of cholesterol, 7-Ketocholesterol (7KCh), causes cellular oxidative damage. In the present study, we investigated the physiological responses of cardiomyocytes to 7KCh. A 7KCh treatment inhibited the growth of cardiac cells and their mitochondrial oxygen consumption. It wa...

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Detalles Bibliográficos
Autores principales:	Cheng, Mei-Ling, Yang, Cheng-Hung, Wu, Pei-Ting, Li, Yi-Chin, Sun, Hao-Wei, Lin, Gigin, Ho, Hung-Yao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002498/ https://www.ncbi.nlm.nih.gov/pubmed/36901848 http://dx.doi.org/10.3390/ijms24054418

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