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Analysis of Dysferlin Direct Interactions with Putative Repair Proteins Links Apoptotic Signaling to Ca(2+) Elevation via PDCD6 and FKBP8

Quantitative surface plasmon resonance (SPR) was utilized to determine binding strength and calcium dependence of direct interactions between dysferlin and proteins likely to mediate skeletal muscle repair, interrupted in limb girdle muscular dystrophy type 2B/R2. Dysferlin canonical C2A (cC2A) and...

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Detalles Bibliográficos
Autores principales: Drescher, Dennis G., Drescher, Marian J., Selvakumar, Dakshnamurthy, Annam, Neeraja P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002499/
https://www.ncbi.nlm.nih.gov/pubmed/36902136
http://dx.doi.org/10.3390/ijms24054707