G-Quadruplexes Regulate miRNA Biogenesis in Live Zebrafish Embryos

RNA guanine quadruplexes (G4s) regulate RNA functions, metabolism, and processing. G4s formed within precursors of microRNAs (pre-miRNAs) may impair pre-miRNAs maturation by Dicer, thus repressing mature miRNA biogenesis. As miRNAs are essential for proper embryonic development, we studied the role...

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Detalles Bibliográficos
Autores principales: Steeman, Tomás J., Weiner, Andrea M. J., David, Aldana P., Binolfi, Andrés, Calcaterra, Nora B., Armas, Pablo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002522/
https://www.ncbi.nlm.nih.gov/pubmed/36902262
http://dx.doi.org/10.3390/ijms24054828

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