Characterization of a PIP Binding Site in the N-Terminal Domain of V-ATPase a4 and Its Role in Plasma Membrane Association

Vacuolar ATPases (V-ATPases) are multi-subunit ATP-dependent proton pumps necessary for cellular functions, including pH regulation and membrane fusion. The evidence suggests that the V-ATPase a-subunit’s interaction with the membrane signaling lipid phosphatidylinositol (PIPs) regulates the recruit...

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Detalles Bibliográficos
Autores principales: Chu, Anh, Yao, Yeqi, Saffi, Golam T., Chung, Ji Hyun, Botelho, Roberto J., Glibowicka, Miroslawa, Deber, Charles M., Manolson, Morris F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002524/
https://www.ncbi.nlm.nih.gov/pubmed/36902293
http://dx.doi.org/10.3390/ijms24054867

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002524/
https://www.ncbi.nlm.nih.gov/pubmed/36902293
http://dx.doi.org/10.3390/ijms24054867

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