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Targeting Cellular Retinoic Acid Binding Protein 1 with Retinoic Acid-like Compounds to Mitigate Motor Neuron Degeneration
All-trans-retinoic Acid (atRA) is the principal active metabolite of Vitamin A, essential for various biological processes. The activities of atRA are mediated by nuclear RA receptors (RARs) to alter gene expression (canonical activities) or by cellular retinoic acid binding protein 1 (CRABP1) to ra...
Autores principales: | Nhieu, Jennifer, Milbauer, Liming, Lerdall, Thomas, Najjar, Fatimah, Wei, Chin-Wen, Ishida, Ryosuke, Ma, Yue, Kagechika, Hiroyuki, Wei, Li-Na |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002585/ https://www.ncbi.nlm.nih.gov/pubmed/36902410 http://dx.doi.org/10.3390/ijms24054980 |
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