Transposable element RNA dysregulation in mutant KRAS(G12C) 3D lung cancer spheroids

Mutant KRAS regulates transposable element (TE) RNA and interferon-stimulated gene (ISG) expression, but it remains unclear whether diverse mutations in KRAS affect different TE RNAs throughout the genome. We analyzed the transcriptomes of 3D human lung cancer spheroids that harbor KRAS(G12C) mutati...

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Detalles Bibliográficos
Autores principales: Carrillo, David, Reggiardo, Roman E., Lim, John, Mantalas, Gary, Peddu, Vikas, Kim, Daniel H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002638/
https://www.ncbi.nlm.nih.gov/pubmed/36909578
http://dx.doi.org/10.1101/2023.02.27.530369

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002638/
https://www.ncbi.nlm.nih.gov/pubmed/36909578
http://dx.doi.org/10.1101/2023.02.27.530369

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