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Transposable element RNA dysregulation in mutant KRAS(G12C) 3D lung cancer spheroids
Mutant KRAS regulates transposable element (TE) RNA and interferon-stimulated gene (ISG) expression, but it remains unclear whether diverse mutations in KRAS affect different TE RNAs throughout the genome. We analyzed the transcriptomes of 3D human lung cancer spheroids that harbor KRAS(G12C) mutati...
Autores principales: | Carrillo, David, Reggiardo, Roman E., Lim, John, Mantalas, Gary, Peddu, Vikas, Kim, Daniel H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002638/ https://www.ncbi.nlm.nih.gov/pubmed/36909578 http://dx.doi.org/10.1101/2023.02.27.530369 |
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