Blood neurofilament light chain levels are associated with disease progression in a transgenic SCA3 mouse model

Increased neurofilament light (NfL) protein in biofluids is reflective of neurodegeneration and has gained interest as a biomarker across neurodegenerative diseases. In spinocerebellar ataxia type 3 (SCA3), the most common dominantly inherited ataxia, patients exhibit progressive NfL increases in pe...

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Detalles Bibliográficos
Autores principales: Mengel, David, Wellik, Isabel G., Schuster, Kristen H., Jarrah, Sabrina I., Wacker, Madeleine, Ashraf, Naila S., Öz, Gülin, Synofzik, Matthis, do Carmo Costa, Maria, McLoughlin, Hayley S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002656/
https://www.ncbi.nlm.nih.gov/pubmed/36909535
http://dx.doi.org/10.1101/2023.02.28.530463

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