Smaug regulates germ plasm synthesis and primordial germ cell number in Drosophila embryos by repressing the oskar and bruno 1 mRNAs

During Drosophila oogenesis, the Oskar (OSK) RNA-binding protein (RBP) determines the amount of germ plasm that assembles at the posterior pole of the oocyte. Here we identify the mechanisms that regulate the osk mRNA in the early embryo. We show that the Smaug (SMG) RBP is transported into the germ...

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Detalles Bibliográficos
Autores principales: Siddiqui, Najeeb U., Karaiskakis, Angelo, Goldman, Aaron L., Eagle, Whitby V.I., Smibert, Craig A., Gavis, Elizabeth R., Lipshitz, Howard D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10002672/
https://www.ncbi.nlm.nih.gov/pubmed/36909513
http://dx.doi.org/10.1101/2023.02.27.530189

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